Structure of PDB 6ip8 Chain 3P Binding Site BS02

Receptor Information
>6ip8 Chain 3P (length=83) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQ
TVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
Ligand information
>6ip8 Chain zz (length=163) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccccucccgggagagccauaguggucugcggaaccggugaguacaccgga
auugcgagauuugggcgugcccccgcgagacugcuagccgaguaguguug
ggucgcgaaaggccuugugguacugccugauagggugcuugcgagugccc
cgggaggucucgu
..<<<<<<<<<<<.<<<<.<<<<<<<<<<<<..<<<<<<....>>>>>><
<<<....>>>>.<<<<..>>>>>>>>>.>>>>>>>.<<<.....<<....
....>>....>>>....>>>>.>><<<<....>>>><<...((((.>>>>
>>>>>>>.)))).
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ip8 HCV IRES Captures an Actively Translating 80S Ribosome.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		D34 K36 G39 Y41 I43 R80 K82 Q83
Binding residue
(residue number reindexed from 1)		D33 K35 G38 Y40 I42 R79 K81 Q82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0014069 postsynaptic density
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ip8, PDBe:6ip8, PDBj:6ip8
PDBsum6ip8
PubMed31080011
UniProtP42677|RS27_HUMAN Small ribosomal subunit protein eS27 (Gene Name=RPS27)

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