Structure of PDB 1rtp Chain 3 Binding Site BS02

Receptor Information

>1rtp Chain 3 (length=109) Species: 10117 (Rattus rattus)

SMTDLLSAEDIKKAIGAFTAADSFDHKKFFQMVGLKKKSADDVKKVFHIL
DKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVE
EFSTLVAES

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1rtp Chain 3 Residue 111

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1rtp Refined crystal structure of rat parvalbumin, a mammalian alpha-lineage parvalbumin, at 2.0 A resolution.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): D90 D92 D94 K96 E101
• Binding residue (residue number reindexed from 1): D90 D92 D94 K96 E101
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005509 calcium ion binding
• GO:0042802 identical protein binding
• GO:0044877 protein-containing complex binding
• GO:0046872 metal ion binding

Biological Process

• GO:0010467 gene expression
• GO:0090102 cochlea development
• GO:0098976 excitatory chemical synaptic transmission
• GO:0098977 inhibitory chemical synaptic transmission

Cellular Component

• GO:0005737 cytoplasm
• GO:0030424 axon
• GO:0032420 stereocilium
• GO:0032437 cuticular plate
• GO:0032991 protein-containing complex
• GO:0043025 neuronal cell body
• GO:0043195 terminal bouton

External links

• PDB: RCSB:1rtp, PDBe:1rtp, PDBj:1rtp
• PDBsum: 1rtp
• PubMed: 8289291
• UniProt: P02625|PRVA_RAT Parvalbumin alpha (Gene Name=Pvalb)