Structure of PDB 8vtx Chain 2m Binding Site BS02
Receptor Information
>8vtx Chain 2m (length=122) Species:
300852
(Thermus thermophilus HB8) [
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RIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAE
VVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQR
TRTNARTRKGPRKTVAGKKKAP
Ligand information
>8vtx Chain 2w (length=72) [
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cccggauagcucagggagagcaggggauugaaaauccccguguccuuggu
ucgauuccgaguccgggcacca
<<<<<<..<<<<.....>>>>.<<<<<<.....>>>>>>.....<<<<<.
......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB
8vtx
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
K120 A123
Binding residue
(residue number reindexed from 1)
K118 A121
External links
PDB
RCSB:8vtx
,
PDBe:8vtx
,
PDBj:8vtx
PDBsum
8vtx
PubMed
39039256
UniProt
P80377
|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)
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