Structure of PDB 8vtv Chain 2m Binding Site BS02
Receptor Information
>8vtv Chain 2m (length=122) Species:
300852
(Thermus thermophilus HB8) [
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RIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAE
VVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQR
TRTNARTRKGPRKTVAGKKKAP
Ligand information
>8vtv Chain 2x (length=77) [
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cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB
8vtv
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.55 Å
Binding residue
(original residue number in PDB)
A118 K121
Binding residue
(residue number reindexed from 1)
A116 K119
External links
PDB
RCSB:8vtv
,
PDBe:8vtv
,
PDBj:8vtv
PDBsum
8vtv
PubMed
39039256
UniProt
P80377
|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)
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