Structure of PDB 8ev6 Chain 2i Binding Site BS02

Receptor Information
>8ev6 Chain 2i (length=127) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLR
AVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGF
LTRDARVVERKKYGKHKARRAPQYSKR
Ligand information
>8ev6 Chain 2x (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgggguggagcagccugguagcucgucgggcucauaacccgaaggucgu
cgguucaaauccggcccccgcaacca
<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB8ev6 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
Resolution2.946 Å
Binding residue
(original residue number in PDB)
K127 R128
Binding residue
(residue number reindexed from 1)
K126 R127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ev6, PDBe:8ev6, PDBj:8ev6
PDBsum8ev6
PubMed37537169
UniProtP80374|RS9_THET8 Small ribosomal subunit protein uS9 (Gene Name=rpsI)

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