Structure of PDB 6ip5 Chain 2i Binding Site BS02

Receptor Information
>6ip5 Chain 2i (length=105) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QVIQF
Ligand information
>6ip5 Chain zu (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcucguuggucuagggguaugauucucgcuuagggugcgagaggucccg
gguucaaaucccggacgagccccca
<<<<<<<..<<<.........>>><<<<<<.......>>>>>>....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB6ip5 HCV IRES Captures an Actively Translating 80S Ribosome.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		Y41 K53 P54 I55 F56
Binding residue
(residue number reindexed from 1)		Y40 K52 P53 I54 F55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6ip5, PDBe:6ip5, PDBj:6ip5
PDBsum6ip5
PubMed31080011
UniProtP83881|RL36A_HUMAN Large ribosomal subunit protein eL42 (Gene Name=RPL36A)

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