Structure of PDB 8vtx Chain 2g Binding Site BS02

Receptor Information
>8vtx Chain 2g (length=155) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW
Ligand information
>8vtx Chain 2y (length=73) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccggauagcucagggagagcaggggauugaaaauccccguguccuugg
uucgauuccgaguccgggcacca
<<<<<<<..<<<<.....>>>>.<<<<<<<...>>>>>>>.....<<<<<
.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB8vtx Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Q86 R143 M144 A147
Binding residue
(residue number reindexed from 1)		Q85 R142 M143 A146
External links
PDB RCSB:8vtx, PDBe:8vtx, PDBj:8vtx
PDBsum8vtx
PubMed39039256
UniProtP17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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