Structure of PDB 8uvs Chain 2S Binding Site BS02
Receptor Information
>8uvs Chain 2S (length=110) Species:
300852
(Thermus thermophilus HB8) [
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RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSAS
SLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALA
EGAREGGLEF
Ligand information
>8uvs Chain 2B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.....<.<<<<<<<<....>>>>>>>>..
.>...>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
8uvs
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Resolution
2.75 Å
Binding residue
(original residue number in PDB)
R15 R25 F29 R30 S31 L32 Y36 Q38 V46 T47 G60 N61 K62 T63 K93 H95 R97
Binding residue
(residue number reindexed from 1)
R13 R23 F27 R28 S29 L30 Y34 Q36 V44 T45 G58 N59 K60 T61 K91 H93 R95
External links
PDB
RCSB:8uvs
,
PDBe:8uvs
,
PDBj:8uvs
PDBsum
8uvs
PubMed
38165935
UniProt
Q5SHQ4
|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)
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