Structure of PDB 4y4p Chain 2S Binding Site BS02

Receptor Information
>4y4p Chain 2S (length=110) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSAS
SLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALA
EGAREGGLEF
Ligand information
>4y4p Chain 2B (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB4y4p Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R15 R25 F29 S31 L32 K33 Y36 Q38 G45 V46 T47 S50 L54 G60 N61 K62 T63 K93 H95 G96 R97
Binding residue
(residue number reindexed from 1)		R13 R23 F27 S29 L30 K31 Y34 Q36 G43 V44 T45 S48 L52 G58 N59 K60 T61 K91 H93 G94 R95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4y4p, PDBe:4y4p, PDBj:4y4p
PDBsum4y4p
PubMed25775268
UniProtQ5SHQ4|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)

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