Structure of PDB 8vtx Chain 2Q Binding Site BS02
Receptor Information
>8vtx Chain 2Q (length=141) Species:
300852
(Thermus thermophilus HB8) [
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MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAA
RVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPG
RVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ
Ligand information
>8vtx Chain 2B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.....<.<<<<<<<<....>>>>>>>>..
.>...>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
8vtx
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R16 L17 G19
Binding residue
(residue number reindexed from 1)
R16 L17 G19
External links
PDB
RCSB:8vtx
,
PDBe:8vtx
,
PDBj:8vtx
PDBsum
8vtx
PubMed
39039256
UniProt
P60489
|RL16_THET8 Large ribosomal subunit protein uL16 (Gene Name=rplP)
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