Structure of PDB 8uvs Chain 2G Binding Site BS02
Receptor Information
>8uvs Chain 2G (length=181) Species:
300852
(Thermus thermophilus HB8) [
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PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDAR
ILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWI
FLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDA
LRGMDIAVVTTAETDEEARALLELLGFPFRK
Ligand information
>8uvs Chain 2B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.....<.<<<<<<<<....>>>>>>>>..
.>...>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
8uvs
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Resolution
2.75 Å
Binding residue
(original residue number in PDB)
P2 N27 V28 W29 E30 Q66 K67 P68 A69 V70 R91 V92 T93 R95 R98
Binding residue
(residue number reindexed from 1)
P1 N26 V27 W28 E29 Q65 K66 P67 A68 V69 R90 V91 T92 R94 R97
External links
PDB
RCSB:8uvs
,
PDBe:8uvs
,
PDBj:8uvs
PDBsum
8uvs
PubMed
38165935
UniProt
Q5SHQ0
|RL5_THET8 Large ribosomal subunit protein uL5 (Gene Name=rplE)
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