Structure of PDB 8uvr Chain 2G Binding Site BS02
Receptor Information
>8uvr Chain 2G (length=181) Species:
300852
(Thermus thermophilus HB8) [
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PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDAR
ILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWI
FLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDA
LRGMDIAVVTTAETDEEARALLELLGFPFRK
Ligand information
>8uvr Chain 2B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
8uvr
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
N27 W29 Q66 K67 A69 V70 R91 V92 T93 R95 R96
Binding residue
(residue number reindexed from 1)
N26 W28 Q65 K66 A68 V69 R90 V91 T92 R94 R95
External links
PDB
RCSB:8uvr
,
PDBe:8uvr
,
PDBj:8uvr
PDBsum
8uvr
PubMed
38165935
UniProt
Q5SHQ0
|RL5_THET8 Large ribosomal subunit protein uL5 (Gene Name=rplE)
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