Structure of PDB 6ip6 Chain 2A Binding Site BS02
Receptor Information
>6ip6 Chain 2A (length=225) Species:
9606
(Homo sapiens) [
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NFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMAR
MARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFV
KLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNA
LIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKK
TTHFVEGGDAGNREDQINRLIRRMN
Ligand information
>6ip6 Chain 1B (length=120) [
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gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu
<<<<<<<<<....<<<<<<<<.....<<<<<<............>>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB
6ip6
HCV IRES Captures an Actively Translating 80S Ribosome.
Resolution
4.5 Å
Binding residue
(original residue number in PDB)
R134 V228
Binding residue
(residue number reindexed from 1)
R111 V205
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003723
RNA binding
GO:0003729
mRNA binding
GO:0003735
structural constituent of ribosome
GO:0005515
protein binding
GO:0042802
identical protein binding
Biological Process
GO:0000463
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181
cytoplasmic translation
GO:0006364
rRNA processing
GO:0006412
translation
GO:0042273
ribosomal large subunit biogenesis
Cellular Component
GO:0005634
nucleus
GO:0005730
nucleolus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005840
ribosome
GO:0005925
focal adhesion
GO:0014069
postsynaptic density
GO:0016020
membrane
GO:0022625
cytosolic large ribosomal subunit
GO:0022626
cytosolic ribosome
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:6ip6
,
PDBe:6ip6
,
PDBj:6ip6
PDBsum
6ip6
PubMed
31080011
UniProt
P18124
|RL7_HUMAN Large ribosomal subunit protein uL30 (Gene Name=RPL7)
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