Structure of PDB 4zer Chain 23 Binding Site BS02
Receptor Information
>4zer Chain 23 (length=59) Species:
300852
(Thermus thermophilus HB8) [
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PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA
HLVRVEVVE
Ligand information
>4zer Chain 2B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.....<.<<<<<<<<....>>>>>>>>..
.>...>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
4zer
The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
Y15 Q19 H52
Binding residue
(residue number reindexed from 1)
Y14 Q18 H51
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0015934
large ribosomal subunit
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:4zer
,
PDBe:4zer
,
PDBj:4zer
PDBsum
4zer
PubMed
25984971
UniProt
Q5SHQ6
|RL30_THET8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)
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