Structure of PDB 8vty Chain 20 Binding Site BS02
Receptor Information
>8vty Chain 20 (length=77) Species:
300852
(Thermus thermophilus HB8) [
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GSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDF
TLFALVDGVVEFQDRGRLGRYVHVRPL
Ligand information
>8vty Chain 2B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.....<.<<<<<<<<....>>>>>>>>..
.>...>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
8vty
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R72 G73 R74 L75
Binding residue
(residue number reindexed from 1)
R65 G66 R67 L68
External links
PDB
RCSB:8vty
,
PDBe:8vty
,
PDBj:8vty
PDBsum
8vty
PubMed
39039256
UniProt
P60493
|RL27_THET8 Large ribosomal subunit protein bL27 (Gene Name=rpmA)
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