Structure of PDB 6mti Chain 2 Binding Site BS02

Receptor Information
>6mti Chain 2 (length=279) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK
KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDII
GEFKVPMNTVDFGHVTEEWRDLQSAEKEQEKLGDICFSLRYVPTAGKLTV
VILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNE
SFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWS
DMLANPRRPIAQWHTLQVEEEVDAMLAVK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6mti Chain 2 Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6mti Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin.
Resolution10.4 Å
Binding residue
(original residue number in PDB)		D584 D590 D644 Y645 D646
Binding residue
(residue number reindexed from 1)		D162 D168 D222 Y223 D224
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6mti, PDBe:6mti, PDBj:6mti
PDBsum6mti
PubMed31160571
UniProtP21707|SYT1_RAT Synaptotagmin-1 (Gene Name=Syt1)

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