Structure of PDB 6xhy Chain 1g Binding Site BS02

Receptor Information

>6xhy Chain 1g (length=155) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW

Ligand information

>6xhy Chain 1y (length=74) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gcccggauagcucaggguagagcaggggauugaaaauccccguguccuug
guucgauuccgaguccgggcacca

<<<<<<<..<<<<......>>>>.<<<<<<.....>>>>>>.....<<<<
<.......>>>>>>>>>>>>....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6xhy Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Resolution	2.6 Å
Binding residue (original residue number in PDB)	N84 Q86 D140 R143 M144 A147 N148
Binding residue (residue number reindexed from 1)	N83 Q85 D139 R142 M143 A146 N147

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:6xhy, PDBe:6xhy, PDBj:6xhy
PDBsum	6xhy
PubMed	33462493
UniProt	P17291\|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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