Structure of PDB 8uvs Chain 1Z Binding Site BS02
Receptor Information
>8uvs Chain 1Z (length=154) Species:
300852
(Thermus thermophilus HB8) [
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MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVEIHRDILVKVSPRNIPEFIEVDVIGDSLHASDLKLPPGVELAVSP
EETI
Ligand information
>8uvs Chain 1B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
8uvs
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Resolution
2.75 Å
Binding residue
(original residue number in PDB)
R10 P15 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 D87
Binding residue
(residue number reindexed from 1)
R10 P15 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 D87
External links
PDB
RCSB:8uvs
,
PDBe:8uvs
,
PDBj:8uvs
PDBsum
8uvs
PubMed
38165935
UniProt
Q5SHZ1
|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)
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