Structure of PDB 8uvr Chain 1S Binding Site BS02
Receptor Information
>8uvr Chain 1S (length=110) Species:
300852
(Thermus thermophilus HB8) [
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RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSAS
SLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALA
EGAREGGLEF
Ligand information
>8uvr Chain 1B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
8uvr
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R15 K19 R25 F29 R30 S31 L32 Y36 Q38 G45 V46 T47 S50 L54 K62 T63 Y92 K93 H95 G96 R97
Binding residue
(residue number reindexed from 1)
R13 K17 R23 F27 R28 S29 L30 Y34 Q36 G43 V44 T45 S48 L52 K60 T61 Y90 K91 H93 G94 R95
External links
PDB
RCSB:8uvr
,
PDBe:8uvr
,
PDBj:8uvr
PDBsum
8uvr
PubMed
38165935
UniProt
Q5SHQ4
|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)
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