Structure of PDB 9b00 Chain 1G Binding Site BS02
Receptor Information
>9b00 Chain 1G (length=181) Species:
300852
(Thermus thermophilus HB8) [
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PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDAR
ILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWI
FLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDA
LRGMDIAVVTTAETDEEARALLELLGFPFRK
Ligand information
>9b00 Chain 1B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.....<.<<<<<<<<....>>>>>>>>..
.>...>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
9b00
Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
P2 N27 V28 W29 E30 K67 V70 R91 V92 T93 R95 R98
Binding residue
(residue number reindexed from 1)
P1 N26 V27 W28 E29 K66 V69 R90 V91 T92 R94 R97
External links
PDB
RCSB:9b00
,
PDBe:9b00
,
PDBj:9b00
PDBsum
9b00
PubMed
39019034
UniProt
Q5SHQ0
|RL5_THET8 Large ribosomal subunit protein uL5 (Gene Name=rplE)
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