Structure of PDB 8vtw Chain 10 Binding Site BS02
Receptor Information
>8vtw Chain 10 (length=83) Species:
300852
(Thermus thermophilus HB8) [
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AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNV
GMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL
Ligand information
>8vtw Chain 1B (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
.<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
8vtw
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.35 Å
Binding residue
(original residue number in PDB)
R72 R74
Binding residue
(residue number reindexed from 1)
R71 R73
External links
PDB
RCSB:8vtw
,
PDBe:8vtw
,
PDBj:8vtw
PDBsum
8vtw
PubMed
39039256
UniProt
P60493
|RL27_THET8 Large ribosomal subunit protein bL27 (Gene Name=rpmA)
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