Structure of PDB 8fni Chain 10 Binding Site BS02

Receptor Information
>8fni Chain 10 (length=416) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLPVSYSPGSVTSTAITAHCDVLSECVAKADELAVQLKTQEGMEEFVEEL
KTSATNEMTALVKQMQTTPLLQRAGMHELRRTLYYTTSLKERDWLEEKQY
TAAMRMLTVEVLRRDGDGVLSADDVLYVTTHVVTANFYNRHLWNRMEKSL
LKFSNYENIDMSSVKAFSTRLFKTRRGCAKETLDIRRKVLLAMSRRVGVL
ANDFDLPSLLGVLQCYTVHDLTPFHLEPLAIRATNHVGDFTPHECATLAH
VLRKWRTMRLEVCERLVERICTSDQLTHHMANAAMIAIRTCFNQVSDGGR
NAMNAEPTRQKLRAMGEQIGCRLDEVEYPALPVILSILDVVVTLKIYVPK
KCLQVIFSQANDMVAIVMEQKDDPITAEEGRQLQALLSHYGNDLAPELSQ
RMKEAFREGVLPDEAS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8fni Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R195 R196 Y199 Y200 Y242 K280 S283 T284 F287 R291 S323 G326 Q329 V333 T362 H365 R368 K369 R374 R404
Binding residue
(residue number reindexed from 1)		R80 R81 Y84 Y85 Y127 K165 S168 T169 F172 R176 S208 G211 Q214 V218 T247 H250 R253 K254 R259 R289
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0016554 cytidine to uridine editing
GO:0048255 mRNA stabilization
Cellular Component
GO:0005739 mitochondrion
GO:0031019 mitochondrial mRNA editing complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fni, PDBe:8fni, PDBj:8fni
PDBsum8fni
PubMed37410820
UniProtQ57VS6

[Back to BioLiP]