Structure of PDB 8fnc Chain 10 Binding Site BS02

Receptor Information
>8fnc Chain 10 (length=416) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLPVSYSPGSVTSTAITAHCDVLSECVAKADELAVQLKTQEGMEEFVEEL
KTSATNEMTALVKQMQTTPLLQRAGMHELRRTLYYTTSLKERDWLEEKQY
TAAMRMLTVEVLRRDGDGVLSADDVLYVTTHVVTANFYNRHLWNRMEKSL
LKFSNYENIDMSSVKAFSTRLFKTRRGCAKETLDIRRKVLLAMSRRVGVL
ANDFDLPSLLGVLQCYTVHDLTPFHLEPLAIRATNHVGDFTPHECATLAH
VLRKWRTMRLEVCERLVERICTSDQLTHHMANAAMIAIRTCFNQVSDGGR
NAMNAEPTRQKLRAMGEQIGCRLDEVEYPALPVILSILDVVVTLKIYVPK
KCLQVIFSQANDMVAIVMEQKDDPITAEEGRQLQALLSHYGNDLAPELSQ
RMKEAFREGVLPDEAS
Ligand information
Receptor-Ligand Complex Structure
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PDB8fnc Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		R195 R196 Y199 Y200 Y242 K280 S283 T284 F287 K288 R290 R291 G326 V327 Q329 T332 V333 T362 H365 V366 R368 K369 R371 R374 H394 R404 P444 A445
Binding residue
(residue number reindexed from 1)		R80 R81 Y84 Y85 Y127 K165 S168 T169 F172 K173 R175 R176 G211 V212 Q214 T217 V218 T247 H250 V251 R253 K254 R256 R259 H279 R289 P329 A330
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0016554 cytidine to uridine editing
GO:0048255 mRNA stabilization
Cellular Component
GO:0005739 mitochondrion
GO:0031019 mitochondrial mRNA editing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fnc, PDBe:8fnc, PDBj:8fnc
PDBsum8fnc
PubMed37410820
UniProtQ57VS6

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