Structure of PDB 7qi6 Chain 1 Binding Site BS02

Receptor Information
>7qi6 Chain 1 (length=56) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSKSKNILVRMVSEAGTGFCFNTKRNRLREKLTLLHYDPVVKQRVLFVEK
KKIRSL
Ligand information
>7qi6 Chain A (length=1558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccca
cuaccuaaaaaaucccaaacauauaacugaacuccucacacccaauugga
ccaaucuaucacccuauagaagaacuaauguuaguauaaguaacaugaaa
acauucuccuccgcauaagccugcgucagauuaaaacgaacugacaauua
acagcccaauaucuacaaucaaccaacaagucauuauuacccucacuguc
aacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaa
cucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuagcauc
accaguauuagaggcaccgccugcccagugacacauguuuaacggccgcg
guacccuaaccgugcaaagguagcauaaucacuuguuccuuaaauaggga
ccuguaugaauggcuccacgaggguucagcugucucuuacuuuuaaccag
ugaaauugaccugcccgugaagaggcgggcauaacacagcaagacgagaa
gacccuauggagcuuuaauuuauuaaugcaaacaguaccuaacaaaccca
cagguccuaaacuaccaaaccugcauuaaaaauuucgguuggggcgaccu
cggagcagaacccaaccuccgagcaguacaugcuaagacuucaccaguca
aagcgaacuacuauacucaauugauccaauaacuugaccaacggaacaag
uuacccuagggauaacagcgcaauccuauucuagaguccauaucaacaau
aggguuuacgaccucgauguuggaucaggacaucccgauggugcagccgc
uauuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguuc
agaccggaguaauccaggucgguuucuaucuacuuucaaauuccucccug
uacgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccg
uaaaugauaucaucucaacuuaguauuauacccacacccacccaagaaca
ggguuugu
<<<.......<<<<....................................
.<......>...............<<.....>>.............>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>.<.<<<......>>>.>..<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
...........................>...>>>>>>........>>>>>
>...<<<<<......>>>>>.........>>>>>><......<<..<<<.
...>>><<<<..<<<<........<<<<<.<<.....>>.>>>>>.....
.<<<...<<<<.......................>>>>.......>>>..
...<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<...
......<......<<<<<<..<<<.........>>>...<<<<<<.....
........>>>>>>....<<<.<<<..<<<<<....>>>..>>>>><<<<
<<......>>>>>>........<...........<<<<<<.....>>>>>
>.....>....>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>
>.....>.....<<<<<........>>>>>.......<<..<<<.<<...
...<<<<.<<<<<<..<<<<<.<<<<<<<<...............<<<..
..>>>................>>>>>>>>>>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<.....<<<..<<<<.....>>>>.
.>>>...........>>.........<<<....>>>............>>
>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>>
>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>>
>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>...
.<<<<<<<....>>>.>>>>....>>..>>>.>>...<.<<<.<<<....
.............>>>.>>><<<<<...<<<....>>>.>>>>>......
<<<................>>>......>..........<<<<.......
>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qi6 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Resolution2.98 Å
Binding residue
(original residue number in PDB)		K10 K14 N15 R19 C29 N31 T32 L43 L44 H45 Y46 R53 I62 R63
Binding residue
(residue number reindexed from 1)		K1 K5 N6 R10 C20 N22 T23 L34 L35 H36 Y37 R44 I53 R54
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qi6, PDBe:7qi6, PDBj:7qi6
PDBsum7qi6
PubMed38769321
UniProtO75394|RM33_HUMAN Large ribosomal subunit protein bL33m (Gene Name=MRPL33)

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