Structure of PDB 6grh Chain 1 Binding Site BS02

Receptor Information
>6grh Chain 1 (length=284) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MINILPFEIISRNTKTLLITYISSVDITHEGMKKVLESLRSKQGIISEYL
LDKLLDESLIDKDKGKEFLITTGVINKTKTSPLWVNSVIISDVPHLFSNA
REQWKCDGVFVSHIIDIKDNNINVSDSTLIWLHLENYHSDIVKRIYSKFE
SNPGVAFIQSYYLKESFRIDGVYSPDLGTPCHFCHIERWLSREEKSFRRN
EMSWANLLQLLKKYQMTLPALALGESERGFSYHLIKRRLQELTGTSLVKS
HVDNFMSSVSADLITCILCKEPVIHWQACSCLER
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6grh Chain 1 Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6grh Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		C192 C195 C290 C292
Binding residue
(residue number reindexed from 1)		C181 C184 C279 C281
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0017000 antibiotic biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6grh, PDBe:6grh, PDBj:6grh
PDBsum6grh
PubMed30661981
UniProtP23184|MCBB_ECOLX Microcin B17-processing protein McbB (Gene Name=mcbB)

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