Structure of PDB 8pj5 Chain 0 Binding Site BS02

Receptor Information
>8pj5 Chain 0 (length=622) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKIL
DKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGM
LIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKK
CPFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEF
AQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSK
RLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIV
TQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLL
VAYKEDEIPVLKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFL
KTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEM
ADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQKQEEFKHIAVFPCKIKILP
QYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEINHKQV
DVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWF
RDEMQKSDWQLIVELKKVFEII
Ligand information
>8pj5 Chain w (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcagaguggcgcagcggaagcgugcugggcccauaacccagaggucgau
ggaucgaaaccauccucugcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj5 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution2.9 Å
Binding residue
(original residue number in PDB)		F1102 N1103 S1104 R1105 S1140 E1142 C1158 K1160 E1167 S1168 R1174
Binding residue
(residue number reindexed from 1)		F504 N505 S506 R507 S542 E544 C560 K562 E569 S570 R576
External links
PDB RCSB:8pj5, PDBe:8pj5, PDBj:8pj5
PDBsum8pj5
PubMed
UniProtO60841|IF2P_HUMAN Eukaryotic translation initiation factor 5B (Gene Name=EIF5B)

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