Structure of PDB 8d8k Chain 0 Binding Site BS02

Receptor Information
>8d8k Chain 0 (length=429) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNNLRRVATNYYK
EIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFK
PQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILS
RQLIMTNLRSSIPASKEYDLIILTHQLLHDGNQFPIQVDENIEHYLNILA
PGGHIVIIERGNPMGFEIIARARQITLRPENFPDEFGKIPRPWNYFLKVI
APCPHQRKCPLQVGNPNFYTHKEGKDLKFCNFQKSIKRPKFSIELKKGKL
LATSWDNGRDYEILNYSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGS
LGDDTQNSWPRIINDPVKRKGHVMMDLCAPSGELEKWTVSRSFSKQIYHD
ARKSKKGDLWASAAKTQIKGLGDLNVKKF
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8d8k Chain 0 Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8d8k Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution3.13 Å
Binding residue
(original residue number in PDB)		R324 P372 C373 H375 C379 P380 L381 C400 C513
Binding residue
(residue number reindexed from 1)		R223 P252 C253 H255 C259 P260 L261 C280 C378
Annotation score4
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0180026 mitochondrial small ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8d8k, PDBe:8d8k, PDBj:8d8k
PDBsum8d8k
PubMed36482135
UniProtP36056|RT22_YEAST Ribosome assembly protein RSM22, mitochondrial (Gene Name=RSM22)

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