Structure of PDB 8q5i Chain z Binding Site BS01 |
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| >8q5i Chain 1 (length=3073)
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ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguaccgggcc
agcaucgguuuggagcggcaggauaauggcggaggaauguggcacggcuu
cugcuguguguuauagccucugacgauacugccagccuagaccgaggacu
gcgguuuuuaccuaggauguuggcauaaugaucuuaagucgcccgucuug
aaacacggaccaaggagucuaacgucuaugcgaguguuuggguguaaaac
ccguacgcguaaugaaagugaacgaaggugggggcccauuagggugcacc
aucgaccgauccugauguguucggauggauuugaguaagagcauagcugu
ugggacccgaaagauggugaacuaugccugaauagggugaagccagagga
aacucugguggaggcucguagcgguucugacgugcaaaucgaucgucgaa
uuuggguauaggggcgaaagacuaaucgaaccaucuaguagcugguuccu
gccgaaguuucccucaggauagcagaagcucguaucaguuuuaugaggua
aagcgaaugauuagaagucuugggcuuaacuuauucucaaacuuuaaaua
uguaagaaguccuuguugcuuaauugaacguggacaauugaaugaagagc
uuuuagugggccauuuuugguaagcagaacuggcgaugcgggaugaaccg
aacgugaaguuaaagugccggaaugcacgcucaucagacaccacaaaagg
uguuaguucaucuagacagccggccgaaugaacuagcccugaaaauggau
ggcgcucaagcgugcuacuuauacuucaccgugauugcuguuuugacgcu
uucacgaguaggcaggcguggaggucagugacgaagccuuugcuguaaag
cugggucgaacggccucuagugcagaucuuggugguaguagcaaauauuc
aaaugagaacuuugaagacugaaguggggaaagguuccaugucaacagca
guuggacauggguuagucgauccuaagagauggggaagcuccguuucaac
gugcuugauuuuucaggccaaccaucgaaagggaauccgguuaaaauucc
ggaacuuggauauggauucuucacggcaacguaacugaauguggagacgu
cggcgugagcccugggaggaguuaucuuuucuucuuaacagcuuaucacc
cuggaauugguuuauccggagauggggucuuauggcuggaagagcgcggu
aauuuugccgcguccggugcgcuuacgacgguccuugaaaauccacagga
aggaauaguuuucaugccaagucguacucauaaccgcagcaggucuccaa
gguuaacagccucuaguugauagaauaauguagauaagggaagucggcaa
aauagauccguaacuucgggauaaggauuggcucuaaggaucggaacgau
caacuuagaacugguacggacaaggggaaucugacugucuaauuaaaaca
uagcauugugauggucagaaagugauguugacacaaugugauuucugccc
agugcucugaaugucaaagugaagaaauucaaccaagcgcggguaaacgg
cgggaguaacuaugacucucuuaagguagccaaaugccucgucaucuaau
uagugacgcgcaugaauggauuaacgagauucccacugucccuaucuacu
aucuagcgaaaccacagccaagggaacgggcuuggcagaaucagcgggga
aagaagacccuguugagcuugacucuaguuugacauugugaaaaguuuuu
acuuauucaaugaagcggagcuggaggucaaacuccacguucuagcauua
agcccucugggcgauccggguugaagacauugucagguggggaguuuggc
uggggcggcacaucuguuaaacgauaacgcagguguccuaagggggacuc
auggagaacagaaaucuccaguagaacaaaaggguaaaaguccccuugau
uuugauuuucagugugaauacaaaccaugaaaguguggccuaucgauccu
uuagucccucggaauuugaggcuagaggugccagaaaaguuaccacaggg
auaacuggcuuguggcagucaagcguucauagcgacauugcuuuuugauu
cuucgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguu
ggauuguucacccacuaauagggaacgugagcuggguuuagaccgucgug
agacagguuaguuuuacccuacugaugaauguuaucgcaauaguaauuga
acuuaguacgagaggaaccguucauucagauaauugguuuuugcggcugu
cugaucaggcaacgccgcgaagcuaccaucugcuggauuauggcugaacg
ccucuaagucagaauccaugcuagaacgcgaugauuuuugcccugcacau
uuuagauggauacgaauaagacuuuuuagucgcuggaccauagcaggcug
gcaacggugcgcuuagcggaaaggcuuugugcgcuugccggcggauagca
augucaacaugcgcggggauaaauccuuugcauacgacuuagauguacaa
cggaguauuguaagcaguagaguagccuuguuguuacgaucugcugagau
uaagcucuuguugucugauuugu |
.......................<<<<<<.....<......>......>>
>>>.>.........<<....>>..<<<<<......<<.....>>.....>
>>>>..[[[...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<...<<<<<<<<<<<<.<<<<<<<.....<<<<......>>>
>.(.......<<<......)>>>....>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....((((
(..<<<<<<)))))..]]]...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<..>>..<<<
<<<<.<<<<<<<<.<<<<<<<....<<.<<<<<<<......<<<<<<...
...>>>>>>.......>>>>>>.>.>>.>>>>>.>>>>>>>>>>......
..<<<....>>>.....>>>>>>>....>>>>>>>>>>>>..<<<<....
....>>>><<<<<<....<<<<<<.<<<<<<..<<<..<<<<<.....>>
>>>..>>>...<<....>>.......<<<<<..<<<<....>>>>...>>
>>>.<<<<<<<<...<<....>>...>>>.>>>.>>....>>>>>>.>>>
>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<..
..>>>>>>>.....>>>...<<<..<<.<<........>>>>.>>>....
>>>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<<<
<<<....<.<<<....>>>.><<<<<<<<<<...<<<.<<<<<<<.....
<<<....<<<....<<<<...<<..>>.>>>>....>>>..>.>>.....
>>>>>...<<<<.<<<<.<......>>>>>.>>>>.....>>>>>.>>>>
>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>
...<<<<<<<..<<<<(((.....<<<<<<.....<<..........<<<
.<<<<<<<<<<.......<<..>>...>>>>>>>>>>>>>..........
))).>>...>>>>>>.>>>>..>>>>>>><<<<<..<<.........>>.
.>>>>>....>>>>>><.<<<<<<<<.<<......<<<<..<<<....>>
>.>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.....<<<
<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<...
..>>.>>>>>>....((<<<<<<...<<....<<<....>>>........
..<<<<<<....>>>>>>......>>....>>...<<<<<........>>
>>>))<<<<.<<<<<<<.....<<<....>>>.......<<<<<<...<<
<<.<<<<<<<.<<<<<<<<<<..{{{..>>>>>><...<<<<<....<<<
<<<....<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<
......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>...
.......>>>..>>>>>>>>>>>>..>>.....<<......>>>>>>>.<
<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<.........<.
....<<<<<...............>>>>><<.<<<<<<<<<<<...>>>>
>..>>>>>>.>>............<<<<<<<<<..<<<.........>>>
..<<<<<<<....<<<<.....>>>>......>>>>>>>...<<..<<<.
.<<<<<<....<<<.....<<<<....>>>>.....>>>.>>>>..>>>>
><<<<...........>>>>........<...........<<<<<.....
..>>>>>.....>.....>>....>>.>>>>>>>..>..>>.>>>>>>>.
.>>>>>>....>>....<<<<<........>>>>>....[[[[[..{{{.
{{......[[[[.{{[[[[..<<<<<.<<<<<<<<..<<<<<<<.>>>>>
>>...<<<<<.....<<<<..<<<<<......>>>>>.............
.<<<<...>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<<
<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<..
.<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<
<<.<<<<<.......>>>>.>>>>.<<<....>>>.>>))).......((
((((..((((.>>>>>>))))))))))..........]]]]..}}]]]].
......<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>.
>.......<<<<<.<<<<<<..<.<<<<<<<......>>>>>>>...>.<
<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<...
.>>>.>>>>....}}..}}}.]]]]]....<<<<<<<<..<<<<...<<<
<<.................>>>>>..<<<<<...<<<<....<<<<<<<<
<<}}}.>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.....
......>>>>>...>>>>.>>>>....>>>>>>>>.....<<<<<<.<<<
..<....<<..........<<<<....>>>>......>>.......<<<<
<<...<<<<<<<..<<<......>>>..>>>>>>>.>>>>>>........
......>.>>>.>>>>>>..<<<<<<<.............>>....<<<<
<<<<<.<<<....<<<<.<..<<<<<......>>>>>..>>>>>...>>>
....>>>>.>>>>>..>>>>>.. |
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| PDB | 8q5i Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy |
| Resolution | 2.45 Å |
Binding residue
(original residue number in PDB) | A2 N3 L4 R5 T6 K8 R9 L10 G18 K19 R20 K21 W23 L24 P26 S37 R38 S39 R42 K43 K46 E55 T56 V57 H58 S59 R60 S61 R62 A63 R64 K67 K70 R71 R74 H75 G77 Y78 G79 K80 R81 K82 G83 T84 K85 R88 M89 P90 Q92 W95 M96 R97 L99 R100 R103 K104 R110 K114 K117 H118 Y120 H121 Y124 K125 K128 G129 N130 K135 I143 |
Binding residue
(residue number reindexed from 1) | A1 N2 L3 R4 T5 K7 R8 L9 G17 K18 R19 K20 W22 L23 P25 S36 R37 S38 R41 K42 K45 E54 T55 V56 H57 S58 R59 S60 R61 A62 R63 K66 K69 R70 R73 H74 G76 Y77 G78 K79 R80 K81 G82 T83 K84 R87 M88 P89 Q91 W94 M95 R96 L98 R99 R102 K103 R109 K113 K116 H117 Y119 H120 Y123 K124 K127 G128 N129 K134 I142 |
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