Structure of PDB 8rg0 Chain y Binding Site BS01

Receptor Information
>8rg0 Chain y (length=543) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNL
GEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANP
NIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHS
QEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDY
KAHQRQNEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRW
YQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNA
LLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELL
ECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPES
MREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRK
IQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELM
ASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFD
Ligand information
>8rg0 Chain 7 (length=31) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caacaacaacaacaaggauccaaaacagacc
...............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rg0 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution3.4 Å
Binding residue
(original residue number in PDB)		L650 R653 H716 R723
Binding residue
(residue number reindexed from 1)		L318 R321 H384 R391
External links
PDB RCSB:8rg0, PDBe:8rg0, PDBj:8rg0
PDBsum8rg0
PubMed
UniProtQ99613|EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (Gene Name=EIF3C)

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