Structure of PDB 8pj6 Chain y Binding Site BS01

Receptor Information
>8pj6 Chain y (length=531) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNL
GEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANP
NIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHS
QEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDY
KAHQRQNEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRW
YQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNA
LLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELL
ECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPES
MREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRK
IQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELM
ASLDQPTQTVVMHRTEPTAQQNLALQLAEKL
Ligand information
>8pj6 Chain 7 (length=56) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caacaacaacaacaaggauccaaaacagaccaccaugguacguuucaagg
cuugag
..................................................
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj6 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution2.9 Å
Binding residue
(original residue number in PDB)
R653 K712 H716 R719 R734
Binding residue
(residue number reindexed from 1)
R321 K380 H384 R387 R402
External links
PDB RCSB:8pj6, PDBe:8pj6, PDBj:8pj6
PDBsum8pj6
PubMed
UniProtQ99613|EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (Gene Name=EIF3C)

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