Structure of PDB 8pj5 Chain y Binding Site BS01

Receptor Information
>8pj5 Chain y (length=531) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNL
GEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANP
NIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHS
QEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDY
KAHQRQNEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRW
YQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNA
LLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELL
ECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPES
MREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRK
IQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELM
ASLDQPTQTVVMHRTEPTAQQNLALQLAEKL
Ligand information
>8pj5 Chain 7 (length=56) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caacaacaacaacaaggauccaaaacagaccaccaugguacguuucaagg
cuugag
..................................................
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj5 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H465 D635 L650 R653 H716 R719 R723 R734
Binding residue
(residue number reindexed from 1)		H149 D303 L318 R321 H384 R387 R391 R402
External links
PDB RCSB:8pj5, PDBe:8pj5, PDBj:8pj5
PDBsum8pj5
PubMed
UniProtQ99613|EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (Gene Name=EIF3C)

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