Structure of PDB 7naf Chain y Binding Site BS01

Receptor Information
>7naf Chain y (length=167) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MATRTQFENSNEIGVFSKLCLVAVGGSENFYSAFVHTTIAGTRIIGRMTA
GNLLVPTQTTDQELQHLQRVEERLSALGNVICCNDYVALVHPDIDRETEE
LIEVFRQTISGNILVGSYCSGLVHPQTSVQDQLVAGTVNRGSSVVGAGMV
VLAVTGLDTTAPELSVI
Ligand information
>7naf Chain 1 (length=378) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagggugaagccagaggaaacucugguggaggcucgaaaauggaauuag
acugaaggucggcgcccuggaguuaucuuuucuuguuuaucccgcuucgg
ccccaaggugaacagccucuaauguagauaagggaagucgggggaaucug
acuguuaacgagauucccacugucccuaucuacucggggaacuggcuugu
cggcucuuccuaucauaccauucgguaagcguuggauuguucacccacua
auagggaacgugagcugaauugaacuuaggaacaguucauucggauaauu
gguuuuugcggcugucugaucaggcauugccgcgaagcuaccauccgaau
cuauauauuguaagcugagauuaagccu
...<<<....<<<<<<<....>>>>>>>.....>>>..............
.......<<<<........<<<..(((..>>>...............>>>
>....<<<<.....>>>>.....<<<<<<<.<<........<<<<<<<<<
........>>.>>>>>>>.....>>.>>>>>>>.................
.......<<<<..<.<<<......>>>...>.<<<.........>>>...
..>>>>............<.<<<<<<.......>>>>>>.><<<<<...<
<<<....<<<<<<<<<<))).>>>>>..>>>>>...>>>>..>>>>>...
......<<<.........>>>.......
Receptor-Ligand Complex Structure
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PDB7naf Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.13 Å
Binding residue
(original residue number in PDB)		E8 N9 N33
Binding residue
(residue number reindexed from 1)		E8 N9 N29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
GO:0043023 ribosomal large subunit binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0000460 maturation of 5.8S rRNA
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470 maturation of LSU-rRNA
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0042254 ribosome biogenesis
GO:0042256 cytosolic ribosome assembly
GO:0042273 ribosomal large subunit biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7naf, PDBe:7naf, PDBj:7naf
PDBsum7naf
PubMed36482249
UniProtQ12522|IF6_YEAST Eukaryotic translation initiation factor 6 (Gene Name=TIF6)

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