Structure of PDB 7ar7 Chain y Binding Site BS01

Receptor Information

>7ar7 Chain y (length=268) Species: 3702 (Arabidopsis thaliana)

GTLGRAIYTVGNWIRGTGQALDRVGSLLQGSHRIEEHLSRHRTLMNVFDK
SPLVDKDVFVAPSASVIGDVQIGKGSSIWYGCVLRGDVNNISVGSGTNIQ
DNTLVHVAKTNISGKVLPTLIGDNVTVGHSAVIHGCTVEDDAFVGMGATL
LDGVVVEKHAMVAAGSLVKQNTRIPSGEVWGGNPAKFMRKLTDEEIVYIS
QSAKNYINLAQIHASENSKSFEQIEVERALRKKYARKDEDYDSMLGITRE
TPPELILPDNVLPGGKPV

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 7ar7 Chain y Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7ar7 A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
• Resolution: 3.72 Å
• Binding residue (original residue number in PDB): H107 H135
• Binding residue (residue number reindexed from 1): H106 H134
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 4.2.1.-

Gene Ontology

Molecular Function

• GO:0004089 carbonate dehydratase activity
• GO:0005515 protein binding
• GO:0016829 lyase activity
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009853 photorespiration
• GO:0009901 anther dehiscence
• GO:0070207 protein homotrimerization
• GO:2000377 regulation of reactive oxygen species metabolic process

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0016020 membrane
• GO:0031966 mitochondrial membrane
• GO:0045271 respiratory chain complex I

External links

• PDB: RCSB:7ar7, PDBe:7ar7, PDBj:7ar7
• PDBsum: 7ar7
• PubMed: 33768254
• UniProt: Q9C6B3|GCA2_ARATH Gamma carbonic anhydrase 2, mitochondrial (Gene Name=GAMMACA2)