Structure of PDB 5yzg Chain y Binding Site BS01

Receptor Information
>5yzg Chain y (length=112) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARNAEKAMTALARFRQAQLEEPFLASECTELPKAEKWRRQIIGEISKKVA
QIQNAGLGEFRIRDLNDEINKLLREKGHWEQALPPPRKTRAELMKAIDFE
YYGYLDEDDGVI
Ligand information
>5yzg Chain H (length=139) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucgcuucucggccuuuuggcuaagaucaaguguaguaucuguucuuuua
auauguccucuaccgaggacaauauuaaggauuuuuggagcagggagcca
cgcaucgaccugguauugcaguaccuccaggaacggugc
...............................................<<<
<<<<<<<<<<....>>>>>>.>>>>>>>...............<......
><<<<<<.<<<<<.............>>>>>..>>>>>>
Receptor-Ligand Complex Structure
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PDB5yzg Structure of a human catalytic step I spliceosome
Resolution4.1 Å
Binding residue
(original residue number in PDB)		A11 R14
Binding residue
(residue number reindexed from 1)		A10 R13
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000350 generation of catalytic spliceosome for second transesterification step

View graph for
Biological Process
External links
PDB RCSB:5yzg, PDBe:5yzg, PDBj:5yzg
PDBsum5yzg
PubMed29301961
UniProtQ9ULR0|ISY1_HUMAN Pre-mRNA-splicing factor ISY1 homolog (Gene Name=ISY1)

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