Structure of PDB 8ip9 Chain xa Binding Site BS01

Receptor Information
>8ip9 Chain xa (length=70) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELEKLKHKKKRLVQSPNSFFMDVKCQGCFNITTVFSHSQTVVVCPGCQTV
LCQPTGGKARLTEGCSFRRK
Ligand information
>8ip9 Chain aa (length=1695) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugugcaaguaugaaccaauuugaacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguacgugcuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucugggaggggc
gcauuuauuagauaaauccgaugauucaugauaacucgacggaucgcacg
gccuucgugccggcgacgcaucauucaaauuucugcccuaucaacuuucg
augguaggauaggggccuaccaugguggugacgggugacggagaauuagg
guucgauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcgcaaauuacccaauccugacacggggagguagugacaau
aaauaacaauaccgggcgcauuagugucugguaauuggaaugaguacaau
cuaaaucccuuaacgaggauccauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuuaaguuguugcaguuaaaa
agcucguaguuggaccuugggccggccggcaucgcgcuccuagcccggca
ucguuacuuugaagaaauuagagugcucaaagcaagccaucgcucuggau
acauuagcaugggauaacaucauaggauuccgguccuauuguguuggccu
ucgggaucggaguaaugauuaauagggacagucgggggcauucguauuuc
auagucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaa
gcauuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucg
aagacgaucagauaccguccuagucucaaccauaaacgaugccgaccagg
gaucggcggauguugcuuauaggacuccgccggcaccuuaugagaaauca
aagucuuuggguuccggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggcguggagccugcgcuuaauuugacuc
aacacggggaaacuuaccagguccagacauagcaaggauugacagacuga
gagcucuuucuugauucuaugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccguuaacgaacgagaccucagccugc
uaacuagcuaugcggagccaucccuccgcagcuagcuucuuagagggacu
auggccguuuaggccacggaaguuugaggcaauaacaggucugucaugcc
cuuagauguucugggccgcacgcgcgcuacacugauguauucaacgagua
uauagccuuggccgacaggcccggguaaucuugggaaauuucaucgugau
ggggauagaucauugcaauuguuggucuucaacgaggaaugccuaguaag
cgcgagucaucagcucgcguugacuacgucccugcccuuuguacacaccg
cccgucgcuccuaccgauugaaugguccggugaaguguucggaucgcggc
gacggacgucgcgagaaguccauugaaccuuaucauuuagaggaagcaga
agucguaacaagguuuccguaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>..........<<<..<<....>>..>>>.
<...<<<<<<..................>>>>>>.....>...<<<<.<<
<<......>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....
>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>>>>.........<<<....<<<.....>>>..>>>..>....>.
>.....<<<...<.................>...>>>......<<..<..
.........>..>>.........<<<<<((....<.<<<<.....<<..)
)>>.......>>>>>>>>>>..>>>>>>>>>..........<.<((....
.<.<<...<<<.<.....<.<<<<..>>>>.>..................
..<<<<<<.<<.......<<...<.......>...<.......>.....>
>......>>.>>..>>>>........<...<<<<<<<.............
..>>>>>>>...>......>....<<<<<<.<<...<<<<..<<..<<<<
<<<<...<<<......>>>......>>>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<.<<<.<.....>>>>>>>>>>>>..>>>...<<..))>>.
..>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.......<<....
....>>..........<<<<<.<....<<<<<........<<.<<<....
....>>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..<
<<<..<<...<<<<<<<......>>>>>>>.....>>..>>>>.>>....
.<<<<<.....>>>>>........>>>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>......>>>>.>>>.....<<<<.<.......<<..
.....<<<.<<<<....>>>>.>>>....>>........>.>>>>.....
.<....<<<<<<..........>>>>>>....>.....>>>>>>....<<
<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<
..<<.<.<<.<<.<<....<<<<<<<..<<<..<<<<..<...<<<..<<
.......>>..>>>...>..>>>>..>>>..>>>>>>>...>>.>>.>>.
.>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ip9 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		L19 H21 K22 K23 K24 P30 S32 H51 Q53 P68 T69 G70 G71 K72
Binding residue
(residue number reindexed from 1)		L5 H7 K8 K9 K10 P16 S18 H37 Q39 P54 T55 G56 G57 K58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0046872 metal ion binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ip9, PDBe:8ip9, PDBj:8ip9
PDBsum8ip9
PubMed38267667
UniProtW5HZ68

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