Structure of PDB 8jdk Chain x Binding Site BS01

Receptor Information
>8jdk Chain x (length=215) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLK
RTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGR
FTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDS
PLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLY
FYRDPEEIEKEEQAA
Ligand information
>8jdk Chain w (length=1634) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacgacagugaaacugcgaauggcucauuaaauc
aguuaugguuccuuuggucgcucgacuuggauaacugugguaauucuaga
gcuaauacaugccgacgggcgcugacccccuucgcgggggggaugcgugc
auuuaucagauggugacucuagauaaccgccgaucgcacgcgcggcgacg
acccauucgaacgucugcccuaucaacuuucgaugguagucgccgugccu
accauggugaccacgggugacggggaaucaggguucgauuccggagaggg
agccugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauu
acccacucccgacccggggagguagugacgaaaaauaacaauacaggccc
uguaauuggaaugaguccacuuuaaauccuuccgcgaggauccauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguugcugcaguuaaaaagcucguaguuggaucuuuuacuuugaaa
aaauuagaguguucaaagcaggcccgagccgccuggauaccgcagcuagg
aauaauggaauaggaccgcgguucuauuuuguugguuuucggaacugagg
ccaugauuaagagggacggccgggggcauucguauugcgccgcuagaggu
gaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugccaag
aauguuuucauuaaucaagaacgaaagucggagguucgaagacgaucaga
uaccgucguaguuccgaccauaaacgaugccgacuggcgaugcggcggcg
uuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugggu
uccggggggaguaugguugcaaagcugaaacuuaaaggaauugacggaag
ggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggaaa
ccucacccggcccggacacggacaggauugacagauugauagcucuuucu
cgauuccgugggugguggugcauggccguucuuaguugguggagcgauuu
gucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguuac
gcgacccgcggucggcgucccccaacuucuuagagggacaaguggcguuc
agccacccgagauugagcaauaacaggucugugaugcccuuagauguccg
gggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgc
cggcaggcgcggguaacccguugaaccccauucgugauggggaucgggga
uugcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaa
gcuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacu
accgauuggaugguuuagugaggcccucggaucggccccgcgcggagcgc
ugagaagacggucgaacuugacuaucuagaggaaguaaaagucguaacaa
gguuuccguaggugaaccugcggaaggaucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<....>>...>>.>>......<<........<
<<.<....<<....<<<<.........<<.....<<.<<<.....>>>.>
>......>>.........<<<<...<<<<<......>>>>>...>>>><<
..<<<<<....<......>..>>>>>..>>...<<<<.<<..>>>>>>..
>.>>>...>>..>.>>>.<<<....<<<....<<<<<<<.........>>
>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.
<<<..........>>>.>>.<.<<....>>.>...>>>>>>.........
<<<....<<.......>>..>>>..>...>>.>.....<<.<<<.<..>.
.>>>..>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>.
>>>.........<.<((.....<.<<...<<<.<<....<<<<<<.<...
....<<...<.......>.<<<<.......>>>>...>>......>.>>>
..>>>........<.<<.<<<<.<<...............>>.>>>>.>>
.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<..
....>>>......>>>>>>>>..>>.......<<....>>...>>>>..>
..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<....
.>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<
<<<......>>>>>>>>>>.>..>>>...<<..))>>...>>.....>>>
.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<
<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>.....
.....<<<<<.<....<<<<<<.......<<.<<<........>>>.>>.
....>>>>>>.<.<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>
...<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<<<
<<<<<<...>>>>.>>>>.....>>>>..>>>>..>.....<<<<<....
.>>>>>........>>>....>>>.>>>.....>>>>>>>>....>.>>>
>>...>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<
<....>>>>.>>>....>.........>>>.>>......<.....<<<<<
..........>>>>>.....>.....>>>>>.....<<<<<<<<......
.>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<
.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<...<..>.....>>
>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>..
...<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jdk Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		F32 R41 R102 P105 T109 N110 I112 Q132 Y139 R155
Binding residue
(residue number reindexed from 1)		F30 R39 R100 P103 T107 N108 I110 Q130 Y137 R153
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001618 virus receptor activity
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005055 laminin receptor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
GO:0043236 laminin binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0007155 cell adhesion
GO:0046718 symbiont entry into host cell
GO:0140374 antiviral innate immune response
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8jdk, PDBe:8jdk, PDBj:8jdk
PDBsum8jdk
PubMed37992713
UniProtP08865|RSSA_HUMAN Small ribosomal subunit protein uS2 (Gene Name=RPSA)

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