Structure of PDB 8cqw Chain x Binding Site BS01 |
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>8cqw Chain 1 (length=3208)
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ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuuugc gguuuaccgggccagcaucgguuuggagcggcaggauaauggcggaggaa uguggcacggcuucugcuguguguuauagccucugacgauacugccagcc uagaccgaggacugcgguuaccuaggauguuggcauaaugaucuuaaguc gcccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuug gguguaaaacccguacgcguaaugaaagugaacgaaggugggggcccauu agggugcaccaucgaccgauccugauguguucggauggauuugaguaaga gcauagcuguugggacccgaaagauggugaacuaugccugaauaggguga agccagaggaaacucugguggaggcucguagcgguucugacgugcaaauc gaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuagua gcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguu uuaugagguaaagcgaaugauuagaagucuugggguugaaaugaccuuaa cuuauucucaaacuuuaaauauguaagaaguccuuguugcuuaauugaac guggacaauugaaugaagagcuuuuagugggccauuuuugguaagcagaa cuggcgaugcgggaugaaccgaacgugaaguuaaagugccggaaugcacg cucaucagacaccacaaaagguguuaguucaucuagacagccggacggug gccauggaagucggaauccgcuaaggaguguguaacaacucaccggccga augaacuagcccugaaaauggauggcgcucaagcgugcuacuuauacuuc accgugauugcuguuuugacgcuuucacgaguaggcaggcguggagguca gugacgaagccuuugcuguaaagcugggucgaacggccucuagugcagau cuuggugguaguagcaaauauucaaaugagaacuuugaagacugaagugg ggaaagguuccaugucaacagcaguuggacauggguuagucgauccuaag agauggggaagcuccguuucaacgugcuugauuuuucaggccaaccaucg aaagggaauccgguuaaaauuccggaacuuggauauggauucuucacggc aacguaacugaauguggagacgucggcgugagcccugggaggaguuaucu uuucuucuuaacagcuuaucacccuggaauugguuuauccggagaugggg ucuuauggcuggaagagcgcgguaauuuugccgcguccggugcgcuuacg acgguccuugaaaauccacaggaaggaauaguuuucaugccaagucguac ucauaaccgcagcaggucuccaagguuaacagccucuaguugauagaaua auguagauaagggaagucggcaaaauagauccguaacuucgggauaagga uuggcucuaaggaucgguuuaacgaucaacuuagaacugguacggacaag gggaaucugacugucuaauuaaaacauagcauugugauggucagaaagug auguugacacaaugugauuucugcccagugcucugaaugucaaagugaag aaauucaaccaagcgcggguaaacggcgggaguaacuaugacucucuuaa gguagccaaaugccucgucaucuaauuagugacgcgcaugaauggauuaa cgagauucccacugucccuaucuacuaucuagcgaaaccacagccaaggg aacgggcuuggcagaaucagcggggaaagaagacccuguugagcuugacu cuaguuugacauugugaaaagacauggaggguguagaauaagugggagcu ucggccggugaaaccacuaccucuauaguuuuuuuacuuauucaaugaag cggagcuggaggucaaacuccacguucuagcauuaagcccucugggcgau ccggguugaagacauugucagguggggaguuuggcuggggcggcacaucu guuaaacgauaacgcagguguccuaagggggacucauggagaacagaaau cuccaguagaacaaaaggguaaaaguccccuugauuuugauuuucagugu gaauacaaaccaugaaaguguggccuaucgauccuuuagucccucggaau uugaggcuagaggugccagaaaaguuaccacagggauaacuggcuugugg cagucaagcguucauagcgacauugcuuuuugauucuucgaugucggcuc uuccuaucauaccgaagcagaauucgguaagcguuggauuguucacccac uaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuuu acccuacugaugaauguuaucgcaauaguaauugaacuuaguacgagagg aaccguucauucagauaauugguuuuugcggcugucugaucaggcaacgc cgcgaagcuaccaucugcuggauuauggcugaacgccucuaagucagaau ccaugcuagaacgcgaugauuuuugcccugcacauuuuagauggauacga auaagacuuuuuagucgcuggaccauagcaggcuggcaacggugcgcuua gcggaaaggcuuugugcgcuugccggcggauagcaaugucaacaugcgcg gggauaaauccuuugcauacgacuuagauguacaacggaguauuguaagc aguagaguagccuuguuguuacgaucugcugagauuaagcucuuguuguc ugauuugu |
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PDB | 8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement |
Resolution | 3.05 Å |
Binding residue (original residue number in PDB) | V2 Y4 S16 R18 Y21 R23 S25 F26 K27 R30 Q34 K43 Q50 Q55 R56 R62 Y63 S65 S66 I67 G68 R69 G71 Q72 K74 E75 G77 T79 K80 R82 W83 P84 A85 K86 R96 N97 A100 N101 Q118 V119 H121 R126 R127 T129 Y130 R131 A132 H133 G134 R135 N137 A138 Y139 Q140 S141 R167 N169 S170 R171 Q172 G174 R175 S178 R181 L182 |
Binding residue (residue number reindexed from 1) | V1 Y3 S15 R17 Y20 R22 S24 F25 K26 R29 Q33 K42 Q49 Q54 R55 R61 Y62 S64 S65 I66 G67 R68 G70 Q71 K73 E74 G76 T78 K79 R81 W82 P83 A84 K85 R95 N96 A99 N100 Q117 V118 H120 R125 R126 T128 Y129 R130 A131 H132 G133 R134 N136 A137 Y138 Q139 S140 R157 N159 S160 R161 Q162 G164 R165 S168 R171 L172 |
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