Structure of PDB 5zep Chain x Binding Site BS01

Receptor Information
>5zep Chain x (length=100) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEVVVKGRNVEVPDHFRTYVSEKLSRLERFDKTIYLFDVELDHERNRRQR
KNCQHVEITARGRGPVVRGEACADSFYTAFESAVQKLEGRLRRAKDRRKI
Ligand information
>5zep Chain a (length=1506) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac
augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg
gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa
acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg
aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg
ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc
ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu
ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag
ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa
gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc
gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc
ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg
gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu
ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga
aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag
cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua
gguguggguuuccuugggauccgugccguagcuaacgcauuaaguacccc
gccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgggggc
ccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaagaacc
uuaccuggguuugacaugcacaggacgccggcagagaugucgguucccuu
guggccugugugcagguggugcauggcugucgucagcucgugucgugaga
uguuggguuaagucccgcaacgagcgcaacccuugucucauguugccagc
acguuaugguggggacucgugagagacugccggggucaacucggaggaag
guggggaugacgucaagucaucaugccccuuauguccagggcuucacaca
ugcuacaauggccgguacaaagggcugcgaugccgugagguggagcgaau
ccuuucaaagccggucucaguucggaucggggucugcaacucgaccccgu
gaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaauacg
uucccgggccuuguacacaccgcccgucacgucaugaaagucgguaacac
ccgaagccgguggccuaacccuuguggagggagccgucgaaggugggauc
ggcgauugggacgaagucguaacaagguagccguaccggaaggugcggcu
ggauca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>......
<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<....
..>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>.
...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<
<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>
>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>
>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<
<......<<<<....>>>>.....>>>>...<.<<<<<......<<....
>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>>
.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<
<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>>
>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<<
<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<..
..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<
<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<..
<<<<<<<<<<<<...>>>>>>>>>>>>...<<..))>>.....>>>>>>.
>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.<<...
..>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>
>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....<<..<
<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>......
..>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>
>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....
>>>......>>>>>>>......<....<<<<<<<........>>>>>>>.
...>.....>>>>>>....<<<<<<<..........>>>>>>>......>
>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<..<<<
<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>..>>>
>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zep Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		E32 V34 V35 K36 R38 N39 F60 Y65 L66 E70 E74 R75 N76 R77 R78 Q79 R80 K81 E87 R91 R93 G94 P95 R98 E100 Y107 R122 R123 K125 D126 R128 K129 I130
Binding residue
(residue number reindexed from 1)		E2 V4 V5 K6 R8 N9 F30 Y35 L36 E40 E44 R45 N46 R47 R48 Q49 R50 K51 E57 R61 R63 G64 P65 R68 E70 Y77 R92 R93 K95 D96 R98 K99 I100
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0006417 regulation of translation
GO:0044238 primary metabolic process
GO:0045900 negative regulation of translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0022627 cytosolic small ribosomal subunit

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5zep, PDBe:5zep, PDBj:5zep
PDBsum5zep
PubMed30206241
UniProtA0QTK6

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