Structure of PDB 8cqw Chain w Binding Site BS01 |
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>8cqw Chain 1 (length=3208)
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ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuuugc gguuuaccgggccagcaucgguuuggagcggcaggauaauggcggaggaa uguggcacggcuucugcuguguguuauagccucugacgauacugccagcc uagaccgaggacugcgguuaccuaggauguuggcauaaugaucuuaaguc gcccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuug gguguaaaacccguacgcguaaugaaagugaacgaaggugggggcccauu agggugcaccaucgaccgauccugauguguucggauggauuugaguaaga gcauagcuguugggacccgaaagauggugaacuaugccugaauaggguga agccagaggaaacucugguggaggcucguagcgguucugacgugcaaauc gaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuagua gcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguu uuaugagguaaagcgaaugauuagaagucuugggguugaaaugaccuuaa cuuauucucaaacuuuaaauauguaagaaguccuuguugcuuaauugaac guggacaauugaaugaagagcuuuuagugggccauuuuugguaagcagaa cuggcgaugcgggaugaaccgaacgugaaguuaaagugccggaaugcacg cucaucagacaccacaaaagguguuaguucaucuagacagccggacggug gccauggaagucggaauccgcuaaggaguguguaacaacucaccggccga augaacuagcccugaaaauggauggcgcucaagcgugcuacuuauacuuc accgugauugcuguuuugacgcuuucacgaguaggcaggcguggagguca gugacgaagccuuugcuguaaagcugggucgaacggccucuagugcagau cuuggugguaguagcaaauauucaaaugagaacuuugaagacugaagugg ggaaagguuccaugucaacagcaguuggacauggguuagucgauccuaag agauggggaagcuccguuucaacgugcuugauuuuucaggccaaccaucg aaagggaauccgguuaaaauuccggaacuuggauauggauucuucacggc aacguaacugaauguggagacgucggcgugagcccugggaggaguuaucu uuucuucuuaacagcuuaucacccuggaauugguuuauccggagaugggg ucuuauggcuggaagagcgcgguaauuuugccgcguccggugcgcuuacg acgguccuugaaaauccacaggaaggaauaguuuucaugccaagucguac ucauaaccgcagcaggucuccaagguuaacagccucuaguugauagaaua auguagauaagggaagucggcaaaauagauccguaacuucgggauaagga uuggcucuaaggaucgguuuaacgaucaacuuagaacugguacggacaag gggaaucugacugucuaauuaaaacauagcauugugauggucagaaagug auguugacacaaugugauuucugcccagugcucugaaugucaaagugaag aaauucaaccaagcgcggguaaacggcgggaguaacuaugacucucuuaa gguagccaaaugccucgucaucuaauuagugacgcgcaugaauggauuaa cgagauucccacugucccuaucuacuaucuagcgaaaccacagccaaggg aacgggcuuggcagaaucagcggggaaagaagacccuguugagcuugacu cuaguuugacauugugaaaagacauggaggguguagaauaagugggagcu ucggccggugaaaccacuaccucuauaguuuuuuuacuuauucaaugaag cggagcuggaggucaaacuccacguucuagcauuaagcccucugggcgau ccggguugaagacauugucagguggggaguuuggcuggggcggcacaucu guuaaacgauaacgcagguguccuaagggggacucauggagaacagaaau cuccaguagaacaaaaggguaaaaguccccuugauuuugauuuucagugu gaauacaaaccaugaaaguguggccuaucgauccuuuagucccucggaau uugaggcuagaggugccagaaaaguuaccacagggauaacuggcuugugg cagucaagcguucauagcgacauugcuuuuugauucuucgaugucggcuc uuccuaucauaccgaagcagaauucgguaagcguuggauuguucacccac uaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuuu acccuacugaugaauguuaucgcaauaguaauugaacuuaguacgagagg aaccguucauucagauaauugguuuuugcggcugucugaucaggcaacgc cgcgaagcuaccaucugcuggauuauggcugaacgccucuaagucagaau ccaugcuagaacgcgaugauuuuugcccugcacauuuuagauggauacga auaagacuuuuuagucgcuggaccauagcaggcuggcaacggugcgcuua gcggaaaggcuuugugcgcuugccggcggauagcaaugucaacaugcgcg gggauaaauccuuugcauacgacuuagauguacaacggaguauuguaagc aguagaguagccuuguuguuacgaucugcugagauuaagcucuuguuguc ugauuugu |
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PDB | 8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement |
Resolution | 3.05 Å |
Binding residue (original residue number in PDB) | K6 K13 G18 R19 S22 K26 L29 R38 S45 E47 F49 R50 L53 R60 K61 A62 T63 R64 Y65 K67 P71 F72 H73 F74 R75 A84 R86 G87 M88 P90 H91 K92 T93 A94 R95 K97 A98 R102 F106 V109 P111 Y113 D114 K115 K116 K117 R118 V127 R129 L130 K131 R134 K135 G147 K149 Y150 L157 E158 K160 R161 K162 S165 Y168 Y169 K172 K173 |
Binding residue (residue number reindexed from 1) | K5 K12 G17 R18 S21 K25 L28 R37 S44 E46 F48 R49 L52 R59 K60 A61 T62 R63 Y64 K66 P70 F71 H72 F73 R74 A83 R85 G86 M87 P89 H90 K91 T92 A93 R94 K96 A97 R101 F105 V108 P110 Y112 D113 K114 K115 K116 R117 V126 R128 L129 K130 R133 K134 G146 K148 Y149 L156 E157 K159 R160 K161 S164 Y167 Y168 K171 K172 |
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