Structure of PDB 6j6h Chain w Binding Site BS01

Receptor Information
>6j6h Chain w (length=68) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVNPKPFLKGLVNHRVGVKLKFNSTEYRGTLVSTDNYFNLQLNEAEEFVH
GTLGEIFIRCNNVLYIRE
Ligand information
>6j6h Chain L (length=209) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuuu
caguguaacaacuaaugaccucagaggcucaauuuguuacaauacacauu
uuuuggcacccaaaauaggacgggaagagacuuuuaaagugagacgucgc
gacccucgcaggagucguucuugacuuuuuggucgcuugauguuucucuc
uucccguuc
..................................................
...<<<<<<<<.....<.<<<<.>>>>.>....>>>>>>>>.........
..................<<<<<<<<<<.<<<<<.>>>>><<<<<<<<<<
<<.<<......<<<<<<....>>>>>>...>>>>>>..>>>>>>>>..>>
>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB6j6h Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		K32 F33 N47 Y48 N50 R74 N76
Binding residue
(residue number reindexed from 1)		K21 F22 N36 Y37 N39 R59 N61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008266 poly(U) RNA binding
GO:1990935 splicing factor binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0036261 7-methylguanosine cap hypermethylation
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005685 U1 snRNP
GO:0005686 U2 snRNP
GO:0005687 U4 snRNP
GO:0005737 cytoplasm
GO:0034715 pICln-Sm protein complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071013 catalytic step 2 spliceosome
GO:0120114 Sm-like protein family complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j6h, PDBe:6j6h, PDBj:6j6h
PDBsum6j6h
PubMed30879786
UniProtP54999|RUXF_YEAST Small nuclear ribonucleoprotein F (Gene Name=SMX3)

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