Structure of PDB 7ohs Chain v Binding Site BS01

Receptor Information
>7ohs Chain v (length=130) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVRKRKMNRSSVGKATRRNKDKQRKINIQSNPIIAANWDYSLTMAQNYKK
LGLRAKLQTPAGGKETEVVKKLEELASRSQSEREEEWLEKLYKKHGDDYK
KMFFDKKLNIYQQSEGDLKRRLLRWKKRNG
Ligand information
>7ohs Chain 1 (length=1697) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaau
aagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaa
gcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguugua
auuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaac
aggacgucauagagggugagaaucccguguggcgaggagugcgguucuuu
guaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugg
gugguuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaagu
acagugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacg
ugaaauuguugaaagggaagggcauuugaucagacaugguguuuugugcc
cucugcuccuuguggguaggggaaucucgcauuucacugggccagcauca
guuuugguggcaggauaaauccauaggaauguagcuugccucgguaagua
uuauagccugugggaauacugccagcugggacugaggacugcgacguaag
ucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggac
caaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgu
aaugaacgagguuggggccucgcaagaggugcacaaucgaccgauccuga
ggauggauuugguaagagcauagcuguugggacccgaaagauggugaaaa
ccaucuaguagcugguuccugccgaaguuucccucaggauagcagaagcu
cguaucaguuuuaugaguaagaaugaagagcuuuuagugggccauuuuug
guaagcagaacuggcgaugcgggaugaaccgaacguagaguuaaggugcc
ggaauacacgcucaucagaacaaaagguguuaguucaucuagacagccgg
acgguggccauggaagucggaauccgcuaaggaguguguaacaacucacc
ggccgaaugaacuagcccugaggauggcgcucaagcguguuaccuauacu
cuaccgucaggguugauaugaugcccugacgaguaggcaggcguggaggu
cagugacgaagccuagaccguaaggucgggucgaacggccucuagugcag
aucuuggugguaguagcagcgaaaccacagccaagggaacgggcuuggca
gaaucagcggggcagucaagcggcgacauugcuaucauaccgaagcagaa
uucgguaagcgucuacugaugaauguuaccgcaauaguaauugaacuuag
uacgagaggaacaguucauucggauaauugguuuuugcggcugucugauc
aggcauugccgcgaagcuaccauccgcuggauuauggcugaacgccucua
agucagaauccaugcuagaacgcggugaugcuccacacagauggauacga
auaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggugc
acuuggcggaaaggccuugggugcuugcuggcgaauugcaaugcgugggg
auaaaucauuuguauacgacuuagauguacaacgggguauuguaagcagu
agaguagcguuacgcugcugagauuaagccuuuguugucugauuugu
..........................<<<<<<..................
.>>>>>.>.........<<....>>..<<<<<......<<.....>>...
..>>>>>..<<<..<........<<.<<<<<<...>>>>>>.>>......
..>....<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......
>>>>.((......<<<.....))>>>....>>>>>>>>..>>>>>>>>..
..>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<
<<<....>>>>>..>>>.................................
.<<....>>...............<<<......>>>..............
....................<<<<<.<<<<<<.....<<<<...<<<<.<
<<<<<<<<.....>>>>>>>>>.....>>>>...>>>>..<<<<<<<.<<
<<<<<<<<<<<<<......<<<<<<<<......<<<<<......>>>>>.
......>>>>>>>>....>>>>>.>>>>>>>>>>........<<<....>
>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<
<<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>..
.........<<<<<..<<<<<....>>>>>...>>>>>...<<..<<...
....>>...>>......>>>>>>.>>>>>>..<<.<...<<<<<<....>
>>>>>......>.>>..<<<<<<......<<......>>..<<<<<<<<<
.....<<.<<<<<<..>>>>.>>>>...>>>>>>>.>>..<<<<.<.<..
.......>.>.>>>>....<<<......>>>...<<<<<<<..<<<<(((
.....<<<<<<......<......<<<.<<<<<<<<<<.......<<<<<
.<<<...<<.........>>...>>>.........<<......>>...>>
>>>...>>>>>>>>>>>>>......))).>....>>>>>>.>>>>..>>>
>>>><<<<<<<<<.........>>>>>>>>>....>>>>>><..<<<<<<
<.<<......<<<<.<<<<....>>>>>>>>...>>>>>>>>>...>...
..>>>>>><<.....<<.>>....>>....<<<<<........>>>>>..
...<<<......<<<....<<.>>....>>>....<...<<<<<......
>>>>>.....>.....>>>.....<<<<<<<<..<<<<.<.<<<<<<...
..<....>....>>>>>>.><<<<<...<.......<<<<<.........
.......>>>>>......>..>>>>>.<<<<...<<<<<...........
>>>>>...>>>>.>>>>....>>>>>>>>.<<<<<<......<<......
....<<<<<.<....>>>>>>......>>.......<<<<<<...<<<<<
....<<<......>>>....>>>>>.>>>>>>............>>>>>>
.<<<<<<.<.............>.....<<<<<.<<<.<<<.....<<<.
..............>>>....>>>....>>>..>>>>>..>>>>>>.
Receptor-Ligand Complex Structure
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PDB7ohs Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution4.38 Å
Binding residue
(original residue number in PDB)		S3 R5 K6 R7 K16 A17 T18 R19 K22 R26 N29 Q31 P34 T45 A63 G64 G65 K66 R175 S176 S178 R180 E181 W184 Y208 S211 G213 R217 R218
Binding residue
(residue number reindexed from 1)		S1 R3 K4 R5 K14 A15 T16 R17 K20 R24 N27 Q29 P32 T43 A61 G62 G63 K64 R78 S79 S81 R83 E84 W87 Y111 S114 G116 R120 R121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ohs, PDBe:7ohs, PDBj:7ohs
PDBsum7ohs
PubMed34813592
UniProtP40007|NOP16_YEAST Nucleolar protein 16 (Gene Name=NOP16)

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