Structure of PDB 7ods Chain v Binding Site BS01

Receptor Information
>7ods Chain v (length=69) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APWSREAVLSLYRALLRQGRQLRYTDRDFYFASIRREFRKNQKLEDAEAR
ERQLEKGLVFLNGKLGRII
Ligand information
Ligand IDPM8
InChIInChI=1S/C21H41N2O7PS/c1-4-5-6-7-8-9-10-11-18(25)32-15-14-22-17(24)12-13-23-20(27)19(26)21(2,3)16-30-31(28)29/h19,26,31H,4-16H2,1-3H3,(H,22,24)(H,23,27)(H,28,29)/t19-/m0/s1
InChIKeyBPRKYNVKIAROET-IBGZPJMESA-N
SMILES
SoftwareSMILES
CACTVS 3.385CCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO[PH](O)=O
ACDLabs 10.04O=C(SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)O)CCCCCCCCC
OpenEye OEToolkits 1.7.5CCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)O)O
OpenEye OEToolkits 1.7.5CCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@@H](C(C)(C)CO[P@H](=O)O)O
CACTVS 3.385CCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[CH](O)C(C)(C)CO[PH](O)=O
FormulaC21 H41 N2 O7 P S
NameS-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) DECANETHIOATE
ChEMBL
DrugBank
ZINCZINC000058660945
PDB chain7ods Chain w Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ods Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		P3 R6 V9 E38 F39 Q43 R51 Q54 F61
Binding residue
(residue number reindexed from 1)		P2 R5 V8 E37 F38 Q42 R50 Q53 F60
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0140978 mitochondrial large ribosomal subunit binding
Biological Process
GO:0000266 mitochondrial fission
GO:0006417 regulation of translation
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042254 ribosome biogenesis
GO:0070131 positive regulation of mitochondrial translation
GO:1902775 mitochondrial large ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ods, PDBe:7ods, PDBj:7ods
PDBsum7ods
PubMed34135320
UniProtL0R8F8|MIDUO_HUMAN Mitochondrial ribosome and complex I assembly factor AltMIEF1 (Gene Name=MIEF1)

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