Structure of PDB 7o9k Chain v Binding Site BS01

Receptor Information
>7o9k Chain v (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PWSREAVLSLYRALLRQGRQLRYTDRDFYFASIRREFRKNQKLEDAEARE
RQLEKGLVFLNGKLGRII
Ligand information
Ligand IDPNS
InChIInChI=1S/C11H23N2O7PS/c1-11(2,7-20-21(17,18)19)9(15)10(16)13-4-3-8(14)12-5-6-22/h9,15,22H,3-7H2,1-2H3,(H,12,14)(H,13,16)(H2,17,18,19)/t9-/m0/s1
InChIKeyJDMUPRLRUUMCTL-VIFPVBQESA-N
SMILES
SoftwareSMILES
CACTVS 3.341CC(C)(CO[P](O)(O)=O)[C@@H](O)C(=O)NCCC(=O)NCCS
ACDLabs 10.04O=C(NCCS)CCNC(=O)C(O)C(C)(C)COP(=O)(O)O
OpenEye OEToolkits 1.5.0CC(C)(COP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O
OpenEye OEToolkits 1.5.0CC(C)(COP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCS)O
CACTVS 3.341CC(C)(CO[P](O)(O)=O)[CH](O)C(=O)NCCC(=O)NCCS
FormulaC11 H23 N2 O7 P S
Name4'-PHOSPHOPANTETHEINE
ChEMBL
DrugBankDB03912
ZINC
PDB chain7o9k Chain w Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7o9k Structural basis for late maturation steps of the human mitoribosomal large subunit.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		V9 Q43
Binding residue
(residue number reindexed from 1)		V7 Q41
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0140978 mitochondrial large ribosomal subunit binding
Biological Process
GO:0000266 mitochondrial fission
GO:0006417 regulation of translation
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042254 ribosome biogenesis
GO:0070131 positive regulation of mitochondrial translation
GO:1902775 mitochondrial large ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7o9k, PDBe:7o9k, PDBj:7o9k
PDBsum7o9k
PubMed34135318
UniProtL0R8F8|MIDUO_HUMAN Mitochondrial ribosome and complex I assembly factor AltMIEF1 (Gene Name=MIEF1)

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