Structure of PDB 6s13 Chain v Binding Site BS01

Receptor Information
>6s13 Chain v (length=162) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSA
TKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSR
DRGDQIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVY
RRKDGKYGLIQT
Ligand information
>6s13 Chain a (length=1539) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau
...........<.<<<<......<<<..<<<<.<..<<<<<<<.....<<
<.<<....<<..<<..<<<......................>>>..>>>>
.......<<........<<<<<<...<<...<<<<..<..........<<
..<<....>>..>>....................................
........................>..>>>>..>>.>>>>>>.<<<....
<<<....<<<<<<.......>>>>>>..>>>......>>>..<<<<<<<.
.....>>...>>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>....>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>..........................................<<
...........<<<<<........>>>>>............>>.......
......<.((.....<<<<.....<<..))>>.......>>>>..>....
>.>>>>.>>>..........<<<((.....<<<....<<<.<<<<<<..<
<....<<<.......<<<<<<.....>>>>>>.....>>>......>>.>
>>>>>...<<..<.<<....<.<<<<...............<<.......
.>>.........................<<....>>.>>>>>....>>.>
...>>...>>>....>>>....<..<<.........<<<..........>
.>>......>>..>..........<<<<<<..<<..<<<<<<<<......
>>>>>>>>..>>...<...)).>.....>>>>>>.>>>..<<.......<
<<....>>>.....>>...>>>>.>.<....<<<<<<<.....<<<<<..
<<<<<...........<<........>>..........<<<<<<<.....
.<<<<.......<<<<<....>>>>>.....<<.....>>......>>.>
>..<<.<<<...<<<.........<<<<<.<<<....>>>...<<<....
..>>>....>>>>>......<<..<....<........<<......>>..
.....>...>......<<<<.......>>>>.........>>........
.......>>>.>>>>>....>>>>>>>.........>>>>>.......<<
<<<.....<<<..........................>>>.....>>>>>
.............<.<..<..........>..>.>..........>>>>>
......<<<<<<.........>>>>>>............>>>>>>>....
>.............<<<<.<<.......<<..<<<<....<.<<<<..<<
..............>>.>>>>>....>>>>..>>.......>>.>>>>..
.............<<<<<............>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s13 Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Resolution3.58 Å
Binding residue
(original residue number in PDB)		I2 R3 F4 E5 I6 H7 G8 D9 N10 L28 E29 R30 Y31 F32 N33 D34 V35 P36 H41 K45 T46 Y47 S48 K53 E69 Y75 L80 N83 K84 R87 Q88 R90 K91 Y92 R95 N97 R98 K99 S100 R101 D102
Binding residue
(residue number reindexed from 1)		I1 R2 F3 E4 I5 H6 G7 D8 N9 L27 E28 R29 Y30 F31 N32 D33 V34 P35 H40 K44 T45 Y46 S47 K52 E68 Y74 L79 N82 K83 R86 Q87 R89 K90 Y91 R94 N96 R97 K98 S99 R100 D101
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0044238 primary metabolic process

View graph for
Biological Process
External links
PDB RCSB:6s13, PDBe:6s13, PDBj:6s13
PDBsum6s13
PubMed31391518
UniProtD2Z097

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