Structure of PDB 6gqv Chain v Binding Site BS01

Receptor Information
>6gqv Chain v (length=206) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIF
VAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLD
IINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVN
QAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELER
VAKSNR
Ligand information
>6gqv Chain 2 (length=1776) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccggucggauuuccaacggggccuuuccuucuggcuaaccuugagucc
uuguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguu
caaagcaggcguauugcucgaauauauuagcauggaauaauagaauagga
cguuugguucuauuuuguugguuucuaggaccaucguaaugauuaauagg
gacggucgggggcaucaguauucaauugucagaggugaaauucuuggauu
uauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaa
ucaagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucu
uaaccauaaacuaugccgacuagggaucgggugguguuuaugacccacuc
ggcaccuuacgagaaaucaaagucuuuggguucuggggggaguauggucg
caaggcugaaacuuaaaggaauugacggaagggcaccaccaggaguggag
ccugcggcuuaauuugacucaacacggggaaacucaccagguccagacac
aauaaggauugacagauugagagcucuuucuugauuuugugggugguggu
gcauggccguucuuaguugguggagugauuugucugcuuaauugcgauaa
cgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugguuau
ccacuucuuagagggacuaucgguuucaagccgauggaaguuugaggcaa
uaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuacac
ugacggagccagcgagucuaaccuuggccgagaggucuugguaaucuugu
gaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaacg
aggaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccug
cccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagugag
gccucaggaucugcuuagagaagggggcaacuccaucucagagcggagaa
uuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagguuuc
cguaggugaaccugcggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>><...<<<<<<......((((((..<<<....>>>.....<......>
.>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>
>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>.<.<<<..>>>.>...>>>>>>.........<<<....<<<
.....>>>..>>>..>....>.>.....<<<<<<<<<.<<<....>>>.>
>>>>>.>>>......<<<.<...........>>.>>.........<<<<<
((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>
>>>>.........<<<[[.....<.<<...<<<.<<....<<<<<<.<<<
<<............>>>>>.>>>>>>.....<<<<<.........<<<.<
....>>>>.........>>>>>.....<<<<.<<.......<<...<...
....>..<<<.....>>>....>>......>>.>>..>>...........
....<<<<<<<<......)))))).>>>>>>>>.........>>....<<
<<<<.<<...<<<<..<<..<<<<<<.....<<<......>>>.......
.>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>
>...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>
>>>>..........<<<.<<.<<<..<<<<<<<<.<<<...>>>>>>>>>
>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<.
...>>>>....>>>..]]]].}.<<<<.<<<<<<<..<<.<<<<<<..<<
<.<<<<<<......<<........>>..........<<<<<.<....<<<
<.........<<.<<<........>>>.>>.......>>>>....<.<<<
.....<<<<<<....<<<.<<<<......>>...<<<......>>>...>
>.>>>....<<<<..<<..<<<<...<....<..<<......>>..>...
...>...>>>>.>>....<<<<<.......>>>>>........>>>>...
.>>>.>>>.......>>>>......>.>>>>>...>>.>>>>.>>>....
.<<<<<<<......<<.....<<..<<<<....>>>>..>>....>>...
....>>>>>>>...........<<<<<<..........>>>>>>......
....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>
>>>>>>>>.>.....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<
.<<..<...<<<<<<..<<..................>>..>>>>>>...
>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<
<<<<<<....>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gqv Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		R76 N79 K80 R81 F82 R83 K84 R92 N95 L97 N100 G101 N103 N104 G105 K106 K107 L108 K109 A110 R112 N169 F184 R185 N186 I187 T189 I190
Binding residue
(residue number reindexed from 1)		R57 N60 K61 R62 F63 R64 K65 R73 N76 L78 N81 G82 N84 N85 G86 K87 K88 L89 K90 A91 R93 N150 F165 R166 N167 I168 T170 I171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000054 ribosomal subunit export from nucleus
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006450 regulation of translational fidelity
GO:0030490 maturation of SSU-rRNA
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gqv, PDBe:6gqv, PDBj:6gqv
PDBsum6gqv
PubMed29886014
UniProtP26783|RS5_YEAST Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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