Structure of PDB 6c4h Chain v Binding Site BS01

Receptor Information
>6c4h Chain v (length=63) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INPADLRIDVYRTSGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKN
KDQAMKQMKAKLY
Ligand information
>6c4h Chain A (length=636) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaccgacuaauguugaaaaauuagcggaugacuuguggcugggggugaa
aggccaaucaacuauuuagcacacggcgggugcuaacguccgucgaagau
gaaggaacuaggcaaaauggugauaccagcuggcugcaacuguuuauuaa
aaacacagcacugugcaaacacgaaaguggacguauacggugugacgccu
gcccggugccggcgguaaacggccuaagguagcgaaauuccuugucgggu
aaguuccgaccugcacgaauggcguaaugauggccaggcugucuccaccc
gagacucagugaaauugaacucgcugugaagaugcaguguacccgcggca
agacggaaagaccccgugaaccuuuacuauagcuugacugucuggugggu
aguuugacuggggcggucuccuccuaaagaguaacggaggaacggauaaa
agguacuccggggauaacaggcugauaccgcccaagaguucauaucgacg
gcgguguuuggcaccucgaugucggcucaucacauccuggggcugaagua
ggucccaaggguauggcuguucgccauuuaaagugguacgcgagcugggu
uuagaacgucgugagacaguucggucccuaucugcc
...<<<.<<<<<........>>>>>>>>................<<<...
..>>>....................<<<<<<......>>>>>>.......
..<<.........................<<<<<<<<<..<<<.......
..>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.
<<<..<<<<<<.>>>>..>>>>>........<...........<<<<<<.
....>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>......
.....................<<<<<........>>>>>.......<<<.
<<<.<<......<<<<.<<<<<<..<<<<<.<<<.<<<.>>>.>>>..>>
>>>..<<<<.....>>>><<<<<<...........>>>>>>.........
>>>>..>>>>>>.......<<<<...<<<<<<...<<.......>>...>
>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......
>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>.
...<<<<<<<....>>>.>>>>....>>..>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6c4h Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R245 S247 G248 A249 G250 G251 X252 H253 V254 N255 R256 T257 E258 R262 R278 Q280 H281
Binding residue
(residue number reindexed from 1)		R12 S14 G15 A16 G17 G18 X19 H20 V21 N22 R23 T24 E25 R29 R45 Q47 H48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0075523 viral translational frameshifting
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6c4h, PDBe:6c4h, PDBj:6c4h
PDBsum6c4h
PubMed29403017
UniProtP07012|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

[Back to BioLiP]