Structure of PDB 5yzg Chain v Binding Site BS01

Receptor Information
>5yzg Chain v (length=144) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYV
HKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTS
KIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI
Ligand information
>5yzg Chain x (length=25) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LDDDEDRKNPAYIPRKGLFFEHDLR
Receptor-Ligand Complex Structure
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PDB5yzg Structure of a human catalytic step I spliceosome
Resolution4.1 Å
Binding residue
(original residue number in PDB)		H15 K18 F19 K43 V85
Binding residue
(residue number reindexed from 1)		H11 K14 F15 K39 V81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0050684 regulation of mRNA processing
GO:0051028 mRNA transport
GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005829 cytosol
GO:0035145 exon-exon junction complex
GO:0043025 neuronal cell body
GO:0071005 U2-type precatalytic spliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:1990501 exon-exon junction subcomplex mago-y14

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5yzg, PDBe:5yzg, PDBj:5yzg
PDBsum5yzg
PubMed29301961
UniProtQ96A72|MGN2_HUMAN Protein mago nashi homolog 2 (Gene Name=MAGOHB)

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