Structure of PDB 8rg0 Chain u Binding Site BS01

Receptor Information
>8rg0 Chain u (length=603) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPI
MLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEK
TEAAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWV
KFLWESYRQCLDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDN
LRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAF
KAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLY
HLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVE
KQRRLATLLGLQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNP
LKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSI
EFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYA
TREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQH
QLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE
LQK
Ligand information
>8rg0 Chain 7 (length=31) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caacaacaacaacaaggauccaaaacagacc
...............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rg0 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution3.4 Å
Binding residue
(original residue number in PDB)		Y4 E69 Y72 K151 R158 R195 K196
Binding residue
(residue number reindexed from 1)		Y4 E69 Y72 K151 R158 R195 K196
External links
PDB RCSB:8rg0, PDBe:8rg0, PDBj:8rg0
PDBsum8rg0
PubMed
UniProtQ14152|EIF3A_HUMAN Eukaryotic translation initiation factor 3 subunit A (Gene Name=EIF3A)

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