Structure of PDB 7ohy Chain u Binding Site BS01

Receptor Information
>7ohy Chain u (length=116) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIYQCHFCSSPCYPGHGIMFVRNDAKEFRFCRSKCHKAFKQRRNPRKLK
WTKAFRKAAGKELAVDSTLTFAQRRNVPVRYNRELVATTLKAMARIEEIR
QKRERAFYKNRMRGNK
Ligand information
>7ohy Chain 1 (length=1689) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaauaucaauaag
cggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcg
gcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauu
uggagagggcacuuuggggccguuccuugucuauguuccuuggaacagga
cgucauagagggugagaaucccguguggcgaggagugcgguucuuuguaa
agugccuucgaagagucgaguuguuugggaaugcagcucuaagugggugg
uuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacag
ugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaa
auuguugaaagggaagggcauuugaucagacaugguguuuugugcccucu
gcuuaggggaaucucgcauuucacugggccagcaucaguuuugguggcag
gauaaauccauaggaauguagcuugccucgguaaguauuauagccugugg
gaauacugccagcugggacugaggacugcgacguaagucaaggaugcugg
cauaaugguuauaugccgcccgucuugaaacacggaccaaggagucuaac
gucuaugcgaguguuuggguguaaaacccauacgcguaauggugaacgua
gguuggggccucgcaagaggugcacaaucgaccgauccuggauggauuug
guaagagcauagcuguugggacccgaaagauggugaaaaccaucuaguac
ugguuccugccgaaguuucccucaggauagcagaagcucguaucaguuuu
auuaagaaugaagagcuuuuagugggccauuuuugguaagcagaacuggc
gaugcgggaugaaccgaacguagaguuaaggugccggaauacacgcucau
cagaccaaaagguguuaguucaucuagacagccggacgguggccauggaa
gucggaauccgcuaaggaguguguaacaacucaccggccgaaugaacuag
cccuguggcgcucaagcguguuaccuauacucuaccgucaggguugauug
augcccugacgaguaggcaggcguggaggucagugacgaagccuagaccg
uaaggucgggucgaacggccucuagugcagaucuuggugguaguagcagc
gaaaccacagccaagggacgggcuuggcagaaucagcgggcagucgcgac
auugcuauaccgaagcagaauucgguaacccuacugaugaauguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcagccgcgaagcuaccauccgcuggauua
uggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucuu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguagaguagccuuguug
uuacgaucugcugagauuaaccuuuguugucugauuugu
...........................<<<<<.....<...>......>>
>>>...........<<....>>..<<<<<......<<.....>>.....>
>>>>..<<<...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<<<<<.<<<<<<<<<<<<<<<<<.....<<<<......>>>>
.((......<<<.....))>>>....>>>>>>>>>..>>>>>>>.....>
>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<
..>>>>>>..>>>..................................<<.
...>>...............<<<......>>>..................
................<<<<<.<<<<<......<<<<...<<<<.<<<..
......>>>.....>>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<
.....<<<<<<<<<......<<<<<......>>>>>.......>>>>>>>
.>.>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>
>.....>>>>>.>>>>>..<<<<........>>>><<<<<<....<<<<<
<.<<<<<<..<<<...<<<<.....>>>>...>>>...<<.>>.......
<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<.....>>>>>.>
>>....>>>>>>.>>>>>>..<<.<...<<<<<<....>>>>>>.....>
.>>..<<<<<<......<........>..<<<<<<<<<....<<<.<<<<
<.>>>.>>>>>..>>>>>>>.>>..<<<<.<.<<<.....>>>.>.>>>>
....<<<......>>>...<<<<<<<..<<<<(((.....<<<<<<....
.<<......<<<.<<<<<<<<<<.......<<<<<.<<<...<<......
...>>...>>>.........<<......>>...>>>>>...>>>>>>>>>
>>>>..))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......
..>>>>>>>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<.
...>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.>>
....>>....<<<<<.......>>>>>....<<<<<..<<<<<.......
.>>>>>.<<<<<<<......>>>>>>>......>>>>>....<<<<<<<<
..<<<<.<.<<<<<<...............>>>>>>.><<<<<...<<<<
....<<<<<<............>>>>>>...>>>>..>>>>>.<<<<...
<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>.....
..<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<......
.......>.....<<<<<<<<<.<<<......<<................
.......>>.....>>>...>>>.>>>>>>..>>>>>..
Receptor-Ligand Complex Structure
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PDB7ohy Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
H17 I19 S34 K35 K38 Q42 K50 W51 K53 R56 K61 E62 Y108 R111 M112 R113 N115
Binding residue
(residue number reindexed from 1)
H17 I19 S34 K35 K38 Q42 K50 W51 K53 R56 K61 E62 Y108 R111 M112 R113 N115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001671 ATPase activator activity
GO:0051117 ATPase binding
Biological Process
GO:0032781 positive regulation of ATP-dependent activity
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ohy, PDBe:7ohy, PDBj:7ohy
PDBsum7ohy
PubMed34813592
UniProtQ07915|RLP24_YEAST Ribosome biogenesis protein RLP24 (Gene Name=RLP24)

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