Structure of PDB 7ohs Chain u Binding Site BS01

Receptor Information
>7ohs Chain u (length=116) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRIYQCHFCSSPCYPGHGIMFVRNDAKEFRFCRSKCHKAFKQRRNPRKLK
WTKAFRKAAGKELAVDSTLTFAQRRNVPVRYNRELVATTLKAMARIEEIR
QKRERAFYKNRMRGNK
Ligand information
>7ohs Chain 1 (length=1697) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaau
aagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaa
gcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguugua
auuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaac
aggacgucauagagggugagaaucccguguggcgaggagugcgguucuuu
guaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugg
gugguuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaagu
acagugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacg
ugaaauuguugaaagggaagggcauuugaucagacaugguguuuugugcc
cucugcuccuuguggguaggggaaucucgcauuucacugggccagcauca
guuuugguggcaggauaaauccauaggaauguagcuugccucgguaagua
uuauagccugugggaauacugccagcugggacugaggacugcgacguaag
ucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggac
caaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgu
aaugaacgagguuggggccucgcaagaggugcacaaucgaccgauccuga
ggauggauuugguaagagcauagcuguugggacccgaaagauggugaaaa
ccaucuaguagcugguuccugccgaaguuucccucaggauagcagaagcu
cguaucaguuuuaugaguaagaaugaagagcuuuuagugggccauuuuug
guaagcagaacuggcgaugcgggaugaaccgaacguagaguuaaggugcc
ggaauacacgcucaucagaacaaaagguguuaguucaucuagacagccgg
acgguggccauggaagucggaauccgcuaaggaguguguaacaacucacc
ggccgaaugaacuagcccugaggauggcgcucaagcguguuaccuauacu
cuaccgucaggguugauaugaugcccugacgaguaggcaggcguggaggu
cagugacgaagccuagaccguaaggucgggucgaacggccucuagugcag
aucuuggugguaguagcagcgaaaccacagccaagggaacgggcuuggca
gaaucagcggggcagucaagcggcgacauugcuaucauaccgaagcagaa
uucgguaagcgucuacugaugaauguuaccgcaauaguaauugaacuuag
uacgagaggaacaguucauucggauaauugguuuuugcggcugucugauc
aggcauugccgcgaagcuaccauccgcuggauuauggcugaacgccucua
agucagaauccaugcuagaacgcggugaugcuccacacagauggauacga
auaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggugc
acuuggcggaaaggccuugggugcuugcuggcgaauugcaaugcgugggg
auaaaucauuuguauacgacuuagauguacaacgggguauuguaagcagu
agaguagcguuacgcugcugagauuaagccuuuguugucugauuugu
..........................<<<<<<..................
.>>>>>.>.........<<....>>..<<<<<......<<.....>>...
..>>>>>..<<<..<........<<.<<<<<<...>>>>>>.>>......
..>....<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......
>>>>.((......<<<.....))>>>....>>>>>>>>..>>>>>>>>..
..>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<
<<<....>>>>>..>>>.................................
.<<....>>...............<<<......>>>..............
....................<<<<<.<<<<<<.....<<<<...<<<<.<
<<<<<<<<.....>>>>>>>>>.....>>>>...>>>>..<<<<<<<.<<
<<<<<<<<<<<<<......<<<<<<<<......<<<<<......>>>>>.
......>>>>>>>>....>>>>>.>>>>>>>>>>........<<<....>
>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<
<<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>..
.........<<<<<..<<<<<....>>>>>...>>>>>...<<..<<...
....>>...>>......>>>>>>.>>>>>>..<<.<...<<<<<<....>
>>>>>......>.>>..<<<<<<......<<......>>..<<<<<<<<<
.....<<.<<<<<<..>>>>.>>>>...>>>>>>>.>>..<<<<.<.<..
.......>.>.>>>>....<<<......>>>...<<<<<<<..<<<<(((
.....<<<<<<......<......<<<.<<<<<<<<<<.......<<<<<
.<<<...<<.........>>...>>>.........<<......>>...>>
>>>...>>>>>>>>>>>>>......))).>....>>>>>>.>>>>..>>>
>>>><<<<<<<<<.........>>>>>>>>>....>>>>>><..<<<<<<
<.<<......<<<<.<<<<....>>>>>>>>...>>>>>>>>>...>...
..>>>>>><<.....<<.>>....>>....<<<<<........>>>>>..
...<<<......<<<....<<.>>....>>>....<...<<<<<......
>>>>>.....>.....>>>.....<<<<<<<<..<<<<.<.<<<<<<...
..<....>....>>>>>>.><<<<<...<.......<<<<<.........
.......>>>>>......>..>>>>>.<<<<...<<<<<...........
>>>>>...>>>>.>>>>....>>>>>>>>.<<<<<<......<<......
....<<<<<.<....>>>>>>......>>.......<<<<<<...<<<<<
....<<<......>>>....>>>>>.>>>>>>............>>>>>>
.<<<<<<.<.............>.....<<<<<.<<<.<<<.....<<<.
..............>>>....>>>....>>>..>>>>>..>>>>>>.
Receptor-Ligand Complex Structure
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PDB7ohs Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution4.38 Å
Binding residue
(original residue number in PDB)
G16 R33 S34 K35 K38 Q42 K50 W51 K53 R56 K61 E62 R111 N115
Binding residue
(residue number reindexed from 1)
G16 R33 S34 K35 K38 Q42 K50 W51 K53 R56 K61 E62 R111 N115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001671 ATPase activator activity
GO:0051117 ATPase binding
Biological Process
GO:0032781 positive regulation of ATP-dependent activity
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ohs, PDBe:7ohs, PDBj:7ohs
PDBsum7ohs
PubMed34813592
UniProtQ07915|RLP24_YEAST Ribosome biogenesis protein RLP24 (Gene Name=RLP24)

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